{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:27:09Z","timestamp":1777850829562,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2016,9,25]],"date-time":"2016-09-25T00:00:00Z","timestamp":1474761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to describe the ultrasonographic, endoscopic and histological characteristics of the caecum and ileocaecocolic junction in cats suffering from chronic clinical signs compatible with caecocolic disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Cats presenting with clinical signs suggestive of a caecocolic disease were prospectively recruited. All cats underwent an ultrasonographic examination of the caecum, ileum, colon, ileocolic lymph nodes and local mesenteric fat, in addition to comprehensive abdominal ultrasonography. This was followed by a colonoscopy with a macroscopic assessment of the caecocolic mucosa; caecocolic tissue samples were systematically collected for histologic analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighteen cats were included. Eleven of 18 cats had ultrasonographic abnormalities adjacent to the ileocaecocolic junction (lymphadenopathy, local steatitis) and 13\/18 cats had abnormalities directly related to the junction (wall thickening, loss of wall layering). Seventeen of 18 cats had at least one ultrasonographic abnormality. Endoscopically, hyperaemia, oedema, discoloration and\/or erosions were found in all cats. Each cat was classified as having mild or moderate-to-severe lesions according to endoscopic results; no classification could be established statistically for ultrasonographic results. The accentuation of the dimpled pattern tended to be inversely related to the severity of endoscopic lesion scoring. Histologically, a large proportion of cats showed typhlitis (13\/16), one had lymphoma and two were normal. All cats with typhlitis also had colitis. There was only slight agreement between endoscopic and histological caecal results regarding the severity of lesions. Loss of caecal wall layering on ultrasound was found in 7\/18 cats and, surprisingly, did not appear as a reliable predictor of the severity of inflammation or of malignancy; neither did local steatitis nor lymph node size.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and relevance<\/jats:title>\n                    <jats:p>Ultrasonography and endoscopy should not be used as the sole methods to investigate the ileocaecocolic region in cats with clinical signs suggestive of caecocolic disease. The presence of chronic clinical signs should routinely prompt histological biopsy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1098612x16663594","type":"journal-article","created":{"date-parts":[[2016,9,9]],"date-time":"2016-09-09T20:48:21Z","timestamp":1473454101000},"page":"94-104","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Ultrasonographic, endoscopic and histological appearances of the caecum in cats presenting with chronic clinical signs of caecocolic disease"],"prefix":"10.1177","volume":"19","author":[{"given":"Harriet","family":"Hahn","sequence":"first","affiliation":[{"name":"Department of Medical Imaging, University Paris-Est Cr\u00e9teil, National Veterinary School of Alfort, Maisons-Alfort, France"},{"name":"Current address: CHV Fr\u00e9gis, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascaline","family":"Pey","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, University Paris-Est Cr\u00e9teil, National Veterinary School of Alfort, Maisons-Alfort, France"},{"name":"Current address: Antech Imaging Services, 17672-B Cowan Avenue, Irvine, CA 92614, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aur\u00e9lie","family":"Baril","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University Paris-Est Cr\u00e9teil, National Veterinary School of Alfort, Maisons-Alfort, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Charpentier","sequence":"additional","affiliation":[{"name":"Department of Embryology and Histopathology, University Paris-Est Cr\u00e9teil, National Veterinary School of Alfort, Maisons-Alfort, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loic","family":"Desquilbet","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Clinical Epidemiology, University Paris-Est Cr\u00e9teil, National Veterinary School of Alfort, Maisons-Alfort, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Le Poder","sequence":"additional","affiliation":[{"name":"Research Unit of Virology UMR 1161 INRA-ENVA-ANSES, University Paris-Est Cr\u00e9teil, National Veterinary School of Alfort, Maisons-Alfort, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Ch\u00e2teau-Joubert","sequence":"additional","affiliation":[{"name":"Department of Embryology and Histopathology, University Paris-Est Cr\u00e9teil, National Veterinary School of Alfort, Maisons-Alfort, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eve","family":"Laloy","sequence":"additional","affiliation":[{"name":"Department of Embryology and Histopathology, University Paris-Est Cr\u00e9teil, National Veterinary School of Alfort, Maisons-Alfort, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie","family":"Freiche","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University Paris-Est Cr\u00e9teil, National Veterinary School of Alfort, Maisons-Alfort, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,9,25]]},"reference":[{"key":"bibr1-1098612X16663594","first-page":"736","volume-title":"Canine and feline gastroenterology","author":"Gaschen FP","year":"2013"},{"key":"bibr2-1098612X16663594","first-page":"483","volume":"49","author":"Bhandal J","year":"2008","journal-title":"Can Vet 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