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The clinical\n                        consequences of hypertension can be severe, related to \u2018target organ damage\u2019\n                        (eye, heart and vasculature, brain and kidneys), and early diagnosis\n                        followed by appropriate therapeutic management should help reduce the\n                        morbidity associated with this condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical challenges:<\/jats:title>\n                    <jats:p>Despite being a common disease, routine blood pressure (BP) monitoring is\n                        generally performed infrequently, probably leading to underdiagnosis of\n                        feline hypertension in clinical practice. There is a need to: (i) ensure BP\n                        is measured as accurately as possible with a reproducible technique; (ii)\n                        identify and monitor patients at risk of developing hypertension; (iii)\n                        establish appropriate criteria for therapeutic intervention; and (iv)\n                        establish appropriate therapeutic targets. Based on current data, amlodipine\n                        besylate is the treatment of choice to manage feline hypertension and is\n                        effective in the majority of cats, but the dose needed to successfully\n                        manage hypertension varies between individuals. Some cats require long-term\n                        adjuvant therapy and, occasionally, additional therapy is necessary for\n                        emergency management of hypertensive crises.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Evidence base:<\/jats:title>\n                    <jats:p>These Guidelines from the International Society of Feline Medicine (ISFM) are\n                        based on a comprehensive review of the currently available literature, and\n                        are aimed at providing practical recommendations to address the challenges\n                        of feline hypertension for veterinarians. There are many areas where more\n                        data is required which, in the future, will serve to confirm or modify some\n                        of the recommendations in these Guidelines.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1098612x17693500","type":"journal-article","created":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T04:10:16Z","timestamp":1488341416000},"page":"288-303","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":111,"title":["ISFM Consensus Guidelines on the Diagnosis and Management of                    Hypertension in Cats"],"prefix":"10.1177","volume":"19","author":[{"given":"Samantha S","family":"Taylor","sequence":"first","affiliation":[{"name":"International Cat Care\/ISFM, Tisbury,\r                Wiltshire SP3 6LD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew H","family":"Sparkes","sequence":"additional","affiliation":[{"name":"International Cat Care\/ISFM, Tisbury,\r                Wiltshire SP3 6LD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Briscoe","sequence":"additional","affiliation":[{"name":"Animal Referral Hospital, 250 Parramatta\r                Road, Homebush, Sydney, NSW 2140, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Carter","sequence":"additional","affiliation":[{"name":"PO Box 128209, Remuera, Auckland 1541,\r                New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salva Cervantes","family":"Sala","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Felina Barcelona, C\/Marqu\u00e9s de\r                Campo Sagrado 12, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosanne E","family":"Jepson","sequence":"additional","affiliation":[{"name":"Clinical Sciences and Services, Royal\r                Veterinary College, Hawkshead Lane, Hatfield, Hertfordshire, AL9 7TA, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brice S","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Toulouse, ENVT, Toulouse,\r                France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian A","family":"Scansen","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of\r                Clinical Sciences, Colorado State University, Campus Delivery 1678, Fort Collins, CO\r                80523, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,3,1]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2007.tb03005.x"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12600"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2010.11.007"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2010.11.008"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2001.tb02008.x"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2007.tb02982.x"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2000.217.695"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.5772\/36916"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.14562"},{"key":"e_1_3_3_11_1","unstructured":"Brown SA. 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