{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T16:48:33Z","timestamp":1793119713209,"version":"4.5.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,3,21]],"date-time":"2017-03-21T00:00:00Z","timestamp":1490054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The purpose of this study was to determine whether the presence of a splenic mass or a diffusely moth-eaten parenchyma on ultrasonographic scans could represent potential criteria of malignancy in the feline spleen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Feline patients with ultrasonographic images and cytological analysis of the spleen obtained by fine-needle aspiration were retrospectively included in a multicentre study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One hundred and ninety-five cats met our inclusion criteria. There was a lack of agreement between the moth-eaten ultrasonographic appearance of the spleen and the presence of a malignant neoplasia on cytological analysis. The sensitivity and specificity of a moth-eaten parenchyma for predicting malignant neoplastic disease were 13.2% and 84.8%, respectively. The sensitivity and specificity of a splenic mass &gt;1 cm for predicting malignant neoplastic disease were 21.0% and 94.7%, respectively. A marbled appearance of the splenic parenchyma was significantly more frequent among patients examined with a high-frequency transducer (11\u201318 MHz) than among those examined with a low-frequency transducer (6.6\u201310 MHz) (27.6% vs 11.1%, respectively;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.004). Similarly, although not statistically significant, a moth-eaten parenchyma was more frequent in the high-frequency transducer group than in the low-frequency group (17.1% vs 8.9%, respectively;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.09).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and relevance<\/jats:title>\n                    <jats:p>Based on our findings, a moth-eaten ultrasonographic appearance of the spleen in cats does not necessarily reflect a lymphoma or another malignant neoplastic process on cytological analysis. The presence of a splenic mass &gt;1 cm on ultrasound is suggestive of malignancy in cats. Finally, the transducer frequency must be taken into account when assessing the splenic parenchyma, as a high-frequency transducer seems to improve the detection of a marbled or moth-eaten parenchyma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1098612x17697483","type":"journal-article","created":{"date-parts":[[2017,3,21]],"date-time":"2017-03-21T10:10:25Z","timestamp":1490091025000},"page":"23-29","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Association between ultrasonographic appearance of splenic parenchyma and cytology in cats"],"prefix":"10.1177","volume":"20","author":[{"given":"Mileva","family":"Bertal","sequence":"first","affiliation":[{"name":"Department of Medical Imaging, Paris-Est University, National Veterinary School of Alfort, Maisons-Alfort, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Norman Carmel","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, Veterinary Centre Laval, Laval, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Diana","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medical Science, University of Bologna, Ozzano dell\u2019Emilia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loic","family":"Desquilbet","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Clinical Epidemiology, Paris-Est University, National Veterinary School of Alfort, Maisons-Alfort, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swan","family":"Specchi","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, Veterinary Institute of Novara, Granozzo con Monticello, 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