{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T12:44:53Z","timestamp":1792586693812,"version":"4.5.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T00:00:00Z","timestamp":1497830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T00:00:00Z","timestamp":1497830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2018,6]]},"abstract":"\n Objectives<\/jats:title>\n \n Few data are available concerning therapeutic aspects of feline trombiculiasis. This study evaluated the efficacy of a 10% w\/v fipronil-based spot-on solution in 15 cats with natural\n Neotrombicula<\/jats:italic>\n species infestation.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Ten cats received 1 drop per affected site on day (D)0 and D14, with the rest of the 0.5 ml pipette applied on the skin between the shoulders. Five cats served as non-treated controls. Parasite score (0 = absent; 3 = severe, >10 parasites\/zone) was assessed on D0, D14 and D28 on all animals. Skin lesions (SCORing Feline Allergic Dermatitis lesion severity scale [SCORFAD]) and investigator pruritus scale (IPS; 0 = cat comfortable, grooming like any normal cat; 4 = cat uncomfortable, pruritic all the time) were assessed on treated cats on the same days. Global assessment of efficacy, tolerance and ease of use (GAS; 1 = very poor; 5 = excellent) was assessed on D28.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n All the cats completed the study. Parasite scores of the control cats were maintained throughout the trial (mean \u00b1 SD: D0 4 \u00b1 0.7, D14 3.2 \u00b1 1.1 and D28 3.2 \u00b1 0.4). In treated cats, SCORFAD (D0 3.2 \u00b1 5.4, D14 1.1 \u00b1 2.1 [\n P<\/jats:italic>\n <0.002] and D28 0.5 \u00b1 1.3 [\n P<\/jats:italic>\n <0.002]), parasite (D0 3.9 \u00b1 1.3, D14 1.2 \u00b1 0.8 [\n P<\/jats:italic>\n <0.005] and D28 0.4 \u00b1 0.5 [\n P<\/jats:italic>\n <0.005]) and IPS (D0 1 \u00b1 1.2, D14 0.5 \u00b1 1.1 [\n P<\/jats:italic>\n <0.05] and D28 0.3 \u00b1 0.7 [\n P<\/jats:italic>\n <0.05]) scores significantly decreased throughout the trial. On D28, the GAS was 4.2 \u00b1 0.9. There were no adverse effects from treatment.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions and relevance<\/jats:title>\n \n The 10% w\/v fipronil preparation appeared to be effective, safe and practical in the treatment of localised\n Neotrombicula<\/jats:italic>\n species infestation in these cats.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/1098612x17715153","type":"journal-article","created":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T05:17:20Z","timestamp":1497849440000},"page":"587-590","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Treatment of\n Neotrombicula<\/i>\n species infestation in cats using a 10% (w\/v) fipronil topical spot-on formulation: a pilot study"],"prefix":"10.1177","volume":"20","author":[{"given":"Marie C","family":"Cadiergues","sequence":"first","affiliation":[{"name":"UDEAR, Universit\u00e9 de Toulouse, INSERM, ENVT, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christelle","family":"Navarro","sequence":"additional","affiliation":[{"name":"Medical Department, Virbac SA, Carros, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eloy","family":"Castilla-Casta\u00f1o","sequence":"additional","affiliation":[{"name":"Dermatology Service, Small Animal Hospital, Universit\u00e9 de Toulouse, ENVT, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Line A","family":"Lecru","sequence":"additional","affiliation":[{"name":"Dermatology Service, Small Animal Hospital, Universit\u00e9 de Toulouse, ENVT, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charline","family":"Pressanti","sequence":"additional","affiliation":[{"name":"Dermatology Service, Small Animal Hospital, Universit\u00e9 de Toulouse, ENVT, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,6,19]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"495","article-title":"Trombiculiasis: clinical contribution","volume":"15","author":"Guarneri F","year":"2005","unstructured":"Guarneri F, Pugliese A, Giudice E, et al. Trombiculiasis: clinical contribution. Eur J Dermatol 2005; 15: 495\u2013496.","journal-title":"Eur J Dermatol"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1051\/parasite\/2013025"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10493-006-0025-z"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12053"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2004.00414_28.x"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/1751-0147-50-46"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1998.tb03641.x"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2012.01071.x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/484308"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2004.tb00210.x"}],"container-title":["Journal of Feline Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1098612X17715153","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1098612X17715153","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1098612X17715153","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T12:14:46Z","timestamp":1792584886000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1098612X17715153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,19]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1177\/1098612X17715153"],"URL":"https:\/\/doi.org\/10.1177\/1098612x17715153","relation":{},"ISSN":["1098-612X","1532-2750"],"issn-type":[{"value":"1098-612X","type":"print"},{"value":"1532-2750","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,19]]}}}