{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T12:47:16Z","timestamp":1792586836159,"version":"4.5.0"},"reference-count":40,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T00:00:00Z","timestamp":1548115200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UID\/AGR\/04033\/2013"],"award-info":[{"award-number":["UID\/AGR\/04033\/2013"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UID\/MULTI\/00211\/2013"],"award-info":[{"award-number":["UID\/MULTI\/00211\/2013"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim of the study was to investigate retrospectively the prognostic impact of variables such as sex, neuter status, breed, age, number of lesions, location and size of the tumour, tumour extension beyond the nasal planum, ulceration and lymph node status, among others, in a population of cats treated with high-dose rate brachytherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study reviews the outcome of 58 cats with cytologically and\/or histologically confirmed squamous cell carcinoma of the nasal planum, treated at the Clinic Alliance (Bordeaux, France) with high-dose rate brachytherapy from 2010\u20132016. The total radiation dose delivered was 30 Gy, administered in two different schedules: five fractions of 6 Gy for a period of 4 days (Tuesday\u2013Friday) or four fractions of 7.5 Gy for a period of 3 days (Tuesday\u2013 Thursday). Data were collected from cats\u2019 clinical records.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Complete response was achieved in 72% (n = 36) of the cats, partial response in 24% (n = 13) and 2% (n = 1) did not respond. Median progression-free survival and overall survival times were 316 and 835 days, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and relevance<\/jats:title>\n                    <jats:p>\n                      Results indicated that sex (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.045), extension of the tumour from the nasal planum to the upper lip (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.015), tumour size (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.015;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001), the existence of a previous treatment (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.043) and the tumour response to high-dose rate brachytherapy (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.038;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.001) are prognostic factors for cats with squamous cell carcinoma of the nasal planum following high-dose rate brachytherapy.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1098612x18822409","type":"journal-article","created":{"date-parts":[[2019,1,23]],"date-time":"2019-01-23T01:16:59Z","timestamp":1548206219000},"page":"1157-1164","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Prognostic factors for cats with squamous cell carcinoma of the nasal planum following high-dose rate brachytherapy"],"prefix":"10.1177","volume":"21","author":[{"given":"Mafalda","family":"Lino","sequence":"first","affiliation":[{"name":"Department of Veterinary Sciences, University of Tr\u00e1s-os-Montes and Alto Douro, Vila Real, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Lanore","sequence":"additional","affiliation":[{"name":"Veterinary Clinic Alliance, Bordeaux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde","family":"Lajoinie","sequence":"additional","affiliation":[{"name":"Veterinary Clinic Alliance, Bordeaux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Jimenez","sequence":"additional","affiliation":[{"name":"Veterinary Clinic Alliance, Bordeaux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franck","family":"Crouzet","sequence":"additional","affiliation":[{"name":"Veterinary Clinic Alliance, Bordeaux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6130-8381","authenticated-orcid":false,"given":"Felisbina L","family":"Queiroga","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences, University of Tr\u00e1s-os-Montes and Alto Douro, Vila Real, Portugal"},{"name":"Center for the Study of Animal Sciences, Institute of Sciences, Technologies and Agro-environment, University of Porto, Porto, Portugal"},{"name":"Center for Research and Technology of Agro-Environment and Biological Sciences, University of Tr\u00e1s-os-Montes and Alto Douro, Vila Real, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,1,22]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X13483238"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5829.2007.00144.x"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.2009.36911"},{"key":"e_1_3_2_5_2","first-page":"5033","volume-title":"Textbook of veterinary internal medicine","author":"Rassnick KM.","year":"2017","unstructured":"Rassnick KM. Tumors of the skin. In: Ettinger SJ, Feldman EC, C\u00f4t\u00e9 E (eds). Textbook of veterinary internal medicine. St Louis, MO: Elsevier, 2017, pp 5033\u20135045."},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4377-2362-5.00018-9"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2007.00393.x"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1995.206.07.991"},{"key":"e_1_3_2_9_2","first-page":"1107","volume-title":"Pathologic basis of veterinary disease","author":"Hargis AM","year":"2007","unstructured":"Hargis AM, Ginn PE. The integument. In: McGavin MD, Zachary JF (eds). Pathologic basis of veterinary disease. St Louis, MO: Mosby Elsevier, 2007, pp 1107\u20131262."},{"key":"e_1_3_2_10_2","first-page":"432","volume-title":"Withrow and MacEwen\u2019s small animal clinical oncology","author":"Withrow SJ.","year":"2013","unstructured":"Withrow SJ. Tumors of the respiratory system. In: Vail DM, Withrow SJ (eds). Withrow and MacEwen\u2019s small animal clinical oncology. St Louis, MO: Elsevier\/Saunders, 2013, pp 432\u2013462."},{"key":"e_1_3_2_11_2","first-page":"36","article-title":"Prise en charge des tumeurs nasales chez le chien et le chat","author":"Boy\u00e9 P","year":"2016","unstructured":"Boy\u00e9 P, Benoit J. Prise en charge des tumeurs nasales chez le chien et le chat. Le point V\u00e9t\u00e9rinaire, 2016; 369: 36\u201341.","journal-title":"Le point V\u00e9t\u00e9rinaire"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ctsap.2007.03.002"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4377-2362-5.00012-8"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1982.tb01279.x"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2001.tb00988.x"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5810.2004.00040.x"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2006.tb02914.x"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2005.12.003"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.231.5.736"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00411-007-0138-8"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.10.005"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2014.09.016"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.canrad.2016.03.008"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.canrad.2014.08.001"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.canrad.2014.07.156"},{"key":"e_1_3_2_26_2","unstructured":"World Health Organization. Remote-afterloading brachytherapy. http:\/\/www.who.int\/medical_devices\/innovation\/remote_afterloading_brachytherapy.pdf (2011 accessed December 18 2018)."},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5829.2006.00109.x"},{"key":"e_1_3_2_28_2","unstructured":"Owen L World Health Organization. TNM classification of tumours in domestic animals. Geneva: Veterinary Public Health Unit & WHO Collaborating Center for Comparative Oncology 1980."},{"key":"e_1_3_2_29_2","first-page":"e63","volume-title":"Abstracts presented at the ESVONC Annual Congress","author":"de Fornel-Thibaud P","year":"2010","unstructured":"de Fornel-Thibaud P, Lepault S, Delisle F, et al. Use of interstitial brachytherapy (iridium-192) for treatment of fibrosarcomas in cats: 252 cases (2000\u20132004). In: Veterinary and comparative oncology. Abstracts presented at the ESVONC Annual Congress, Turin, Italy, 18\u201320 March 2010. Oxford: Blackwell Publishing, 2011, pp e63\u2013e64."},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.46-1-25"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.22233\/9781905319749.12"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-2800-7.00017-0"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2013.05.009"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9101(1997)20:2<202::AID-LSM12>3.0.CO;2-H"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12025"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/9781118729038.ch5"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X13507071"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2011.03.012"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.1996.57.02.205"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.30072"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-3798"}],"container-title":["Journal of Feline Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1098612X18822409","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1098612X18822409","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1098612X18822409","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T12:26:31Z","timestamp":1792585591000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1098612X18822409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,22]]},"references-count":40,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["10.1177\/1098612X18822409"],"URL":"https:\/\/doi.org\/10.1177\/1098612x18822409","relation":{},"ISSN":["1098-612X","1532-2750"],"issn-type":[{"value":"1098-612X","type":"print"},{"value":"1532-2750","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,22]]}}}