{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:35:27Z","timestamp":1792787727756,"version":"4.5.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2019,8,14]],"date-time":"2019-08-14T00:00:00Z","timestamp":1565740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Society For Theriogenology, Theriogenology Foundation","award":["No grant number\u2014 awarded June 2017"],"award-info":[{"award-number":["No grant number\u2014 awarded June 2017"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>A notable, although relatively uncommon, finding during feline ovariohysterectomy is the presence of parovarian nodules, located proximal to the ovary, near or within the ovarian vascular bundle. They are usually 2\u20133 mm in diameter, white-to-tan in color and glandular in appearance. The objective of this study was to either decisively reinforce the existing findings reported in the literature, which suggest that these parovarian nodules are incidental adrenocortical nodules that are clinically and surgically insignificant, or capture any samples that were not ectopic adrenal tissue in order to characterize them histologically.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Ninety-one formalin-preserved tissue sections containing parovarian nodules were collected during routine feline elective ovariohysterectomy and evaluated histologically.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Definitive histologic information was obtained from 73\/91 (80.2%) submitted samples. Fifty-two of 73 (71.2%) samples were determined to contain accessory adrenal gland cortex. Twenty of 73 (27.4%) samples were determined to contain residual mesonephric structures. While accessory adrenocortical nodules were found bilaterally in cats of all ages, mesonephric structures were predominantly right-sided, and only found in one cat over the age of 1 year. Ectopic or accessory ovarian tissue was not found in any of the samples.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and relevance<\/jats:title>\n                    <jats:p>This study adds to the existing body of data which suggest these nodules are incidental structures that do not need to be removed during surgical sterilization. However, further in vivo studies with larger sample sizes and years of follow-up would be required to more definitively prove this theory.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1098612x19867166","type":"journal-article","created":{"date-parts":[[2019,8,14]],"date-time":"2019-08-14T09:51:11Z","timestamp":1565776271000},"page":"571-574","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Histologic evaluation of parovarian nodules in the cat"],"prefix":"10.1177","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6795-4939","authenticated-orcid":false,"given":"Meghann L","family":"Haase-Berglund","sequence":"first","affiliation":[{"name":"Red Dog Veterinary Relief Services, LLC, Parker, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5497-8616","authenticated-orcid":false,"given":"Ching","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Premanandan","sequence":"additional","affiliation":[{"name":"Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,8,14]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1986.189.01.71"},{"key":"e_1_3_3_3_2","first-page":"322","article-title":"Some heterotropic tissue remnants in domestic animals","volume":"19","author":"Bundza A","year":"1978","unstructured":"Bundza A, Dukes TW. Some heterotropic tissue remnants in domestic animals. Can Vet J 1978; 19: 322\u2013324.","journal-title":"Can Vet J"},{"key":"e_1_3_3_4_2","first-page":"537","article-title":"Ectopic adrenal cortical nodules in the mesorchium of New Zealand white rabbits","volume":"36","author":"Chen H","year":"1986","unstructured":"Chen H. Ectopic adrenal cortical nodules in the mesorchium of New Zealand white rabbits. Lab Anim Sci 1986; 36: 537\u2013538.","journal-title":"Lab Anim Sci"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.147.11.303"},{"key":"e_1_3_3_6_2","first-page":"59","article-title":"On the development of \u201covarian adrenocortical cell nodule\u201d in the horse","volume":"6","author":"Ono H","year":"1969","unstructured":"Ono H, Satoh H, Migake Met al. On the development of \u201covarian adrenocortical cell nodule\u201d in the horse. Exp Rep Equine Health Lab 1969; 6: 59\u201390.","journal-title":"Exp Rep Equine Health Lab"},{"key":"e_1_3_3_7_2","article-title":"Ectopic adrenocortical tissue along the inguinoscrotal path of children","volume":"91","author":"Vaos G","year":"2006","unstructured":"Vaos G, Zavras N, Boukouvalea I. Ectopic adrenocortical tissue along the inguinoscrotal path of children. Int Surg 2006; 91: 125\u2013128.","journal-title":"Int Surg"},{"key":"e_1_3_3_8_2","unstructured":"McEntee K (ed). Reproductive pathology of domestic mammals. New York: Academic Press 1990."},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1043-2760(02)00602-1"},{"key":"e_1_3_3_10_2","first-page":"52","article-title":"Results of seventeen years\u2019 control of hereditary ovarian hypoplasia in cattle of the Swedish Highland breed","volume":"43","author":"Lagerl\u00f6f N","year":"1961","unstructured":"Lagerl\u00f6f N, Settergren I. Results of seventeen years\u2019 control of hereditary ovarian hypoplasia in cattle of the Swedish Highland breed. Cornell Vet 1961; 43: 52\u201364.","journal-title":"Cornell Vet"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)36660-1"},{"key":"e_1_3_3_12_2","first-page":"319","article-title":"Ovarian thecal metaplasia in the adrenal gland","volume":"92","author":"Wong T","year":"1971","unstructured":"Wong T, Warner NE. Ovarian thecal metaplasia in the adrenal gland. Arch Pathol 1971; 92: 319\u2013328.","journal-title":"Arch Pathol"},{"key":"e_1_3_3_13_2","first-page":"E1","article-title":"Suspensory ligament rupture technique during ovariohysterectomy in small animals","volume":"32","author":"Hill LN","year":"2010","unstructured":"Hill LN, Smeak DD. Suspensory ligament rupture technique during ovariohysterectomy in small animals. Compend Contin Educ Vet 2010; 32: E1\u2013E8.","journal-title":"Compend Contin Educ Vet"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.236.5.548"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/104063879500700432"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(91)50056-5"},{"key":"e_1_3_3_17_2","first-page":"22","article-title":"Paraovarian cysts of neoplastic origin are underreported","volume":"13","author":"Smorgick N","year":"2009","unstructured":"Smorgick N, Herman A, Schneider Det al. Paraovarian cysts of neoplastic origin are underreported. JSLS 2009; 13: 22\u201326.","journal-title":"JSLS"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1080\/01926230290105785"},{"key":"e_1_3_3_19_2","first-page":"417","article-title":"Serous cystadenoma of borderline malignancy arising in a parovarian paramesonephric cyst","volume":"27","author":"Puig F","year":"2006","unstructured":"Puig F, Crespo R, Marquina I. Serous cystadenoma of borderline malignancy arising in a parovarian paramesonephric cyst. Eur J Gynaecol Oncol 2006; 27: 417\u2013418.","journal-title":"Eur J Gynaecol Oncol"},{"key":"e_1_3_3_20_2","first-page":"445","article-title":"Parovarian tumors of borderline malignancy","volume":"32","author":"Song MJ","year":"2011","unstructured":"Song MJ, Lee CW, Park EKet al. Parovarian tumors of borderline malignancy. Eur J Gynaecol Oncol 2011; 32: 445\u2013447.","journal-title":"Eur J Gynaecol Oncol"}],"container-title":["Journal of Feline Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1098612X19867166","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1098612X19867166","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1098612X19867166","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T14:57:23Z","timestamp":1792594643000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1098612X19867166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,14]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1177\/1098612X19867166"],"URL":"https:\/\/doi.org\/10.1177\/1098612x19867166","relation":{},"ISSN":["1098-612X","1532-2750"],"issn-type":[{"value":"1098-612X","type":"print"},{"value":"1532-2750","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,14]]}}}