{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T01:12:14Z","timestamp":1792977134601,"version":"4.5.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T00:00:00Z","timestamp":1604361600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim of this retrospective case-control study was to report the efficacy of subcutaneous triamcinolone as part of a regimen for feline eosinophilic keratoconjunctivitis (FEK).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Records and clinical photographs were reviewed and lesions semiquantitatively graded for cats with cytologically confirmed FEK. Clinical data were compared between a study population of nine cats (11 eyes) treated with, and a reference population of seven cats (eight eyes) treated without, a median of 0.11\u2009mg\/kg (range 0.10\u20130.20\u2009mg\/kg) of triamcinolone acetonide subcutaneously.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Breed, sex, age and prevalence of corneal ulceration at presentation; corneal disease severity before and at the initiation of immunomodulation; and duration of antiviral treatment before immunomodulation did not differ significantly between populations (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2a7e0.059). Corneal plaques resolved in five cats each from the study and reference populations (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.366). Median (range) time from immunomodulation to corneal plaque resolution did not significantly differ (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.246) between the study (median 14 days; range 8\u201338 days) and reference (median 28 days, range 14\u201346 days) populations. No adverse reactions were attributed to triamcinolone administration, and all corneal ulcers in the study population re-epithelialized within 14 days (range 8\u201338 days) following triamcinolone injection. Time to corneal ulcer re-epithelialization following triamcinolone injection varied minimally in those receiving antivirals prior to (8 or 30 days until re-epithelialization), simultaneously with (38 days) or after (14 or 24 days) triamcinolone.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and relevance<\/jats:title>\n                    <jats:p>In otherwise healthy cats with FEK, subcutaneous administration of triamcinolone appears to be well tolerated and as efficacious as conventional topical immunomodulatory therapies. It may be especially useful in ulcerated eyes where topical immunomodulation is contraindicated.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1098612x20968660","type":"journal-article","created":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T10:35:45Z","timestamp":1604399745000},"page":"575-583","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Subcutaneous administration of triamcinolone as part of the management of feline eosinophilic keratoconjunctivitis"],"prefix":"10.1177","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7054-3869","authenticated-orcid":false,"given":"Danica R","family":"Lucyshyn","sequence":"first","affiliation":[{"name":"Department of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn L","family":"Good","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly E","family":"Knickelbein","sequence":"additional","affiliation":[{"name":"Veterinary Medical Teaching Hospital, University of California-Davis, Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maggie W","family":"Chang","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, University of California-Davis, Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3878-160X","authenticated-orcid":false,"given":"Ann R","family":"Str\u00f8m","sequence":"additional","affiliation":[{"name":"Veterinary Medical Teaching Hospital, University of California-Davis, Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven R","family":"Hollingsworth","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara M","family":"Thomasy","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA"},{"name":"Department of Ophthalmology and Vision Science, School of Medicine, University of California-Davis, Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2080-8480","authenticated-orcid":false,"given":"Brian C","family":"Leonard","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0103-0127","authenticated-orcid":false,"given":"Lionel","family":"Sebbag","sequence":"additional","affiliation":[{"name":"Veterinary Medical Teaching Hospital, University of California-Davis, Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K Tomo","family":"Wiggans","sequence":"additional","affiliation":[{"name":"Veterinary Medical Teaching Hospital, University of California-Davis, Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6537-4335","authenticated-orcid":false,"given":"David J","family":"Maggs","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,11,3]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"63","article-title":"Feline eosinophilic keratitis: a review of 15 clinical cases.","volume":"23","author":"Paulsen ME","year":"1987","unstructured":"Paulsen ME, Lavach JD, Severin GA, et al. 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