{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T06:09:30Z","timestamp":1784095770879,"version":"3.55.0"},"reference-count":20,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T00:00:00Z","timestamp":1621555200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim of this report was to describe the clinical signs, diagnostic imaging findings, surgical management, histopathological findings, outcome and possible risk factors for cats that developed retroperitoneal fibrosis (RPF) following renal transplantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Medical records of cats that underwent renal transplantation and developed clinically significant RPF between 1995 and 2019 were reviewed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighty-one cats underwent 83 renal transplantations. Of these 81 cats, six developed clinically significant RPF. For all six cats, renal transplantation was performed using cold organ preservation solution and ureteral papilla implantation. Immunosuppression protocol included ciclosporin and prednisolone. All cats had at least one subtherapeutic trough ciclosporin level (&lt;250\u2009ng\/ml) in the postoperative period. Cats presented with moderate-to-severe azotemia 39\u2013210 days following renal transplantation. Abdominal ultrasonography and contrast pyelography revealed various degrees of hydroureter and hydronephrosis of the transplanted kidney. Surgical examination revealed a layer of dense fibrous tissue surrounding the transplanted kidney, ureter and bladder resulting in ureteral obstruction. Ureteral obstruction was managed by reimplantation of the proximal ureter or renal pelvis to the bladder. Histopathologic examination of the fibrous tissue and affected portion of the distal ureter revealed fibrous connective tissue with lymphoplasmacytic infiltration and perivascular inflammation suggestive of an autoimmune type reaction. Of the six cats, two died within 5 days after revision surgery, two developed signs consistent with recurrent partial ureteral obstruction (40 and 41 days after revision), one was euthanized 6 years later for an unrelated disease and one was lost to follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and relevance<\/jats:title>\n                    <jats:p>The incidence of RPF in this population of cats was relatively low (7%), but still represents a significant cause of morbidity and mortality. The cause of RPF remains unknown, although investigation into suboptimal immunosuppression as a potential cause for local rejection reaction is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1098612x211018976","type":"journal-article","created":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T09:52:32Z","timestamp":1621590752000},"page":"304-310","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Retroperitoneal fibrosis as a postoperative complication following renal transplantation in cats"],"prefix":"10.1177","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9878-5894","authenticated-orcid":false,"given":"Brittney J","family":"Byer","sequence":"first","affiliation":[{"name":"Department of Surgical Sciences, University of Wisconsin-Madison, Madison, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J","family":"Hardie","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, University of Wisconsin-Madison, Madison, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan F","family":"McAnulty","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, University of Wisconsin-Madison, Madison, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,5,21]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2016.06.013"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.4103\/0366-6999.152648"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.243.11.1580"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2002.221.984"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/iju.14218"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-019-01759-w"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1973.03220330025006"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000166591"},{"key":"e_1_3_2_10_2","first-page":"334","article-title":"Ureteral stenosis after kidney transplantation: a study on 869 consecutive transplants.","volume":"12","author":"Faenza A","year":"1999","unstructured":"Faenza A, Nardo B, Catena F, et al. Ureteral stenosis after kidney transplantation: a study on 869 consecutive transplants. Transpl Int 1999; 12: 334\u2013340.","journal-title":"Transpl Int"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.12476"},{"key":"e_1_3_2_12_2","article-title":"Retroperitoneal fibrosis; a single-centre case experience with literature review","volume":"3","author":"Adnan S","year":"2019","unstructured":"Adnan S, Bouraoui A, Mehta S, et al. Retroperitoneal fibrosis; a single-centre case experience with literature review.\u2009Rheumatol Adv Pract 2019; 3. DOI: 10.1093\/rap\/rky050.","journal-title":"Rheumatol Adv Pract"},{"key":"e_1_3_2_13_2","first-page":"251","article-title":"Management of idiopathic retroperitoneal fibrosis, a retrospective study at Prince Hussein Urology and Organ Transplantation center (PHUO), Jordan.","volume":"13","author":"Al-Hammouri FA","year":"2019","unstructured":"Al-Hammouri FA, Khori FA, Abu-Qamar AA, et al. Management of idiopathic retroperitoneal fibrosis, a retrospective study at Prince Hussein Urology and Organ Transplantation center (PHUO), Jordan. Iran J Kidney Dis 2019; 13: 251\u2013257.","journal-title":"Iran J Kidney Dis"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.21037\/tau.2018.07.12"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17061974"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.4997\/JRCPE.2019.208"},{"key":"e_1_3_2_17_2","first-page":"187","article-title":"Drug-induced retroperitoneal fibrosis: short aetiopathogenetic note, from the past times of ergot-derivatives large use to currently applied bio-pharmacology.","volume":"36","author":"Alberti C.","year":"2015","unstructured":"Alberti C. Drug-induced retroperitoneal fibrosis: short aetiopathogenetic note, from the past times of ergot-derivatives large use to currently applied bio-pharmacology. G Chir 2015; 36: 187\u2013191.","journal-title":"G Chir"},{"key":"e_1_3_2_18_2","first-page":"159","article-title":"Drugs associated with retroperitoneal fibrosis.","volume":"135","author":"Ristagno RL.","year":"1981","unstructured":"Ristagno RL. Drugs associated with retroperitoneal fibrosis. West J Med 1981; 135: 159\u2013160.","journal-title":"West J Med"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.78.3.330"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.70.127"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cll.2010.10.002"}],"container-title":["Journal of Feline Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1098612X211018976","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1098612X211018976","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1098612X211018976","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T06:03:00Z","timestamp":1784095380000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1098612X211018976"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,21]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1177\/1098612X211018976"],"URL":"https:\/\/doi.org\/10.1177\/1098612x211018976","relation":{},"ISSN":["1098-612X","1532-2750"],"issn-type":[{"value":"1098-612X","type":"print"},{"value":"1532-2750","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,21]]}}}