{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T15:05:34Z","timestamp":1793199934536,"version":"4.5.0"},"reference-count":35,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T00:00:00Z","timestamp":1646697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to describe the epidemiology and clinical presentation of presumed hereditary or presumed breed-related ocular diseases in a population of cats in France.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Medical records from between September 2013 and August 2017 were reviewed to identify cats with at least one presumed hereditary or breed-related ocular disease. Cats with concurrent, or a history of, ocular or systemic infectious diseases were excluded. Signalment, history and clinical findings were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 1161 cats that presented to our institution during the study period, 129 were diagnosed with at least one presumed hereditary or presumed breed-related ocular disease (11.1%, 95% confidence interval [CI] 9.3\u201312.9). Five ocular abnormalities had a prevalence of &gt;1%: entropion, corneal sequestration, persistent pupillary membrane, cataract and retinal dysplasia. The prevalence of entropion was 2.2% (95% CI 1.3\u20133.0), with Persians (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.03), Maine Coons (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.01) and male cats (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.01) being over-represented. The prevalence of corneal sequestration was 2.4% (95% CI 1.5\u20133.3), with Persians (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.01) and Exotic Shorthairs (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.02) being over-represented. Persistent pupillary membranes and cataracts had the same prevalence of 2.3% (95% CI 1.5\u20133.2), with no particular sex or breed significantly over-represented. Retinal dysplasia had a prevalence of 1.6% (95% CI 0.8\u20132.3) and Persian cats were over-represented (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.04). Anterior segment dysgenesis had a low prevalence (0.9%, 95% CI 0.4\u20131.5), with all affected cats being domestic shorthairs and this breed therefore was over-represented (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.04).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and relevance<\/jats:title>\n                    <jats:p>In a French population of cats, presumed hereditary or breed-related ocular diseases accounted for 11.1% of all ocular diseases. Cataracts, corneal sequestration, persistent pupillary membrane, entropion and retinal dysplasia were the most common conditions. Statistical breed over-representation was observed for entropion, corneal sequestration and retinal dysplasia. We recommend that more systematic screening of feline species is conducted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1098612x221080598","type":"journal-article","created":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T08:27:42Z","timestamp":1646728062000},"page":"1274-1282","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Epidemiology and clinical presentation of feline presumed hereditary or breed-related ocular diseases in France: retrospective study of 129 cats"],"prefix":"10.1177","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4910-1844","authenticated-orcid":false,"given":"Matthieu MP","family":"Bott","sequence":"first","affiliation":[{"name":"Ecole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort, CHUV-AC, Ophthalmology Unit, Maisons-Alfort F-94700, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Chahory","sequence":"additional","affiliation":[{"name":"Ecole Nationale V\u00e9t\u00e9rinaire d\u2019Alfort, CHUV-AC, Ophthalmology Unit, Maisons-Alfort F-94700, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,3,8]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ctsap.2004.12.011"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1098-612X(99)90202-4"},{"key":"e_1_3_3_4_2","first-page":"778","volume-title":"Veterinary ophthalmology: two volume set","author":"Petersen-Jones SM","year":"2021","unstructured":"Petersen-Jones SM. Ophthalmic genetics and DNA testing. In: Gelatt KN, Ben-Shlomo G, Gilger BC, et al (eds). Veterinary ophthalmology: two volume set. Hoboken: John Wiley & Sons, 2021, pp 778\u2013787."},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/jhered\/esm019"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-4261"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-16585"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2020.04.005"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00335-014-9517-z"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-016-2595-4"},{"key":"e_1_3_3_11_2","article-title":"A mutation in LTBP2 causes congenital glaucoma in domestic cats (Felis catus).","volume":"11","author":"Kuehn MH","year":"2016","unstructured":"Kuehn MH, Lipsett KA, Menotti-Raymond M, et al. 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Diseases and surgery of the canine anterior uvea. In: Gelatt KN, Ben-Shlomo G, Gilger BC, et al (eds). Veterinary ophthalmology: two volume set. Hoboken: John Wiley & Sons, 2021, pp 1259\u20131316."},{"key":"e_1_3_3_23_2","unstructured":"Chaudieu G Bouhanna L. Ophtalmologie f\u00e9line: atlas and manuel. Paris: Editions Med\u2019Com 2018."},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2011.01081.x"},{"key":"e_1_3_3_25_2","first-page":"519","article-title":"Diagnostic ophthalmology.","volume":"56","author":"Bauer BS","year":"2015","unstructured":"Bauer BS, Sandmeyer LS, Grahn BH. Diagnostic ophthalmology. Can Vet J 2015; 56: 519\u2013520.","journal-title":"Can Vet J"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12567"},{"key":"e_1_3_3_27_2","first-page":"31","article-title":"Posterior nuclear cataracts in two Birman kittens.","volume":"16","author":"Schwinck K","year":"1986","unstructured":"Schwinck K. 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