{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T16:48:00Z","timestamp":1793119680291,"version":"4.5.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T00:00:00Z","timestamp":1658102400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim of this study was to describe the endoscopic appearance of gastroduodenal ulcers (GDUs), and to assess the clinical, ultrasonographic and histological data, as well as long-term follow-up, in cats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The medical record databases of five veterinary endoscopists were evaluated between January 2016 and 2020, in a retrospective study. Cats with at least one gastric or duodenal ulcer detected by endoscopic examination were included. All the medical records of the selected cats were reviewed and information was collected regarding breed, age, sex, neuter status, medical history, clinical signs, and ultrasonographic, endoscopic and histological findings. The cats were evaluated at 6, 12 and 18 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixty-one cats with a median age of 9.0 years (range 2.0\u201316.0) were included in the study. The most common complaints were vomiting (n\u2009=\u200955; 90%) and hyporexia (n\u2009=\u200940; 66%); haematemesis was reported in 12 (20%) cats. Endoscopy showed GDUs in the following locations: gastric body in 28 cats (46%), antropyloric area in 34 cats (56%), fundus in 13 cats (21%) and duodenum in eight cats (13%). A single GDU was found in 42 cats (69%) and multiple GDUs were seen in 19 cats (31%). Histopathological evaluation revealed benign lesions in 33 (54%) cats and malignant lesions in 28 (46%; 24 high-grade lymphoma, one low-grade lymphoma and three carcinoma). High-grade lymphoma was detected only in the stomach. Cats diagnosed with malignant GDUs (median 10.5, range 4\u201316) were significantly older than cats with benign lesions (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.002).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and relevance<\/jats:title>\n                    <jats:p>GDUs are common and were detected in 5.1% of cats undergoing an upper gastrointestinal endoscopy. The risk of a malignant ulcer increases proportionally with each year of increasing age. GDU location, number and morphological appearance do not provide any indication of the nature of the ulcer; however, duodenal ulcers are frequently benign. Endoscopic examination facilitates the early and minimally invasive detection of GDUs in cats.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1098612x221109802","type":"journal-article","created":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T07:06:25Z","timestamp":1658127985000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Gastroduodenal ulceration detected endoscopically in cats: retrospective study of 61 patients"],"prefix":"10.1177","volume":"24","author":[{"given":"Enrico","family":"Bottero","sequence":"first","affiliation":[{"name":"Endovet Professional Association, Turin and Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9336-5150","authenticated-orcid":false,"given":"Alessio","family":"Pierini","sequence":"additional","affiliation":[{"name":"Pisani Carli Chiodo Veterinary Centre, Luni Mare, La Spezia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Ruggiero","sequence":"additional","affiliation":[{"name":"Endovet Professional Association, Turin and Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Cattaneo","sequence":"additional","affiliation":[{"name":"Endovet Professional Association, Turin and Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Campanile","sequence":"additional","affiliation":[{"name":"Endovet Professional Association, Turin and Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Benvenuti","sequence":"additional","affiliation":[{"name":"Endovet Professional Association, Turin and Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,7,18]]},"reference":[{"key":"e_1_3_2_2_2","unstructured":"Guilford WG Strombeck DR. Acute gastritis. In: Guilford WG Center SA Strombeck DR et al (eds). Strombeck\u2019s small animal gastroenterology. 3rd ed. Philadelphia PA: WB Saunders 1996 pp 264\u2013273."},{"key":"e_1_3_2_3_2","unstructured":"Guilford WG Strombeck DR. Chronic gastric diseases. In: Guilford WG Center SA Strombeck DR et al (eds). Strombeck\u2019s small animal gastroenterology. 3rd ed. Philadelphia PA: WB Saunders 1996 pp 284\u2013291."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1053\/jfms.2001.0148"},{"key":"e_1_3_2_5_2","unstructured":"Hall JA. Diseases of the stomach. In: Ettinger SJ Feldman EC (eds). Textbook of veterinary internal medicine: diseases of the dog and cat. 5th ed. 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