{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T22:56:01Z","timestamp":1793228161051,"version":"4.5.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"IVC Evidensia","id":[{"id":"https:\/\/ror.org\/002cx2f43","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2024,12]]},"abstract":"\n Objectives<\/jats:title>\n \n The aim of this retrospective cohort study was to compare two groups of cats with lower respiratory tract disease, one with\n Mycoplasma felis<\/jats:italic>\n detected by PCR in the bronchoalveolar lavage fluid (BALF) (M+) and the other without (M\u2013), with regard to signalment, clinical signs, diagnostic results, treatment response and survival.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n All cats for which\n M felis<\/jats:italic>\n was investigated by PCR in BALF between 2016 and 2023 were included. Cats with evidence of oropharyngeal contamination, or for which PCR results were under the quantification level, or without follow-up information were excluded. Cats that had received antibiotics effective against\n M felis<\/jats:italic>\n before BALF collection were excluded if PCR results were negative. Follow-up information was retrieved from the medical records and by contacting referring veterinarians and owners.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 55 cats were included (19 in the M+ group and 36 in the M\u2013 group). Significant differences were detected between the two groups in the prevalence of systemic signs (M+: 0%, M\u2013: 28%;\n P<\/jats:italic>\n \u2009=\u20090.01), bronchial collapse on bronchoscopy (M+: 28%, M\u2013: 6%;\n P<\/jats:italic>\n \u2009=\u20090.03), radiographic alveolar lesions (M+: 57%, M\u2013: 24%;\n P<\/jats:italic>\n \u2009=\u20090.04), and percentage of neutrophils (M+: 65%, M\u2013: 35%;\n P<\/jats:italic>\n \u2009=\u20090.002) and eosinophils (M+: 9%, M\u2013: 25%;\n P<\/jats:italic>\n \u2009=\u20090.03) in the BALF. Antibiotics were used more frequently in M+ cats (M+: 90%, M\u2013: 42%;\n P<\/jats:italic>\n \u2009=\u20090.001) than in M\u2013 cats. No significant difference was found in treatment response (short term:\n P<\/jats:italic>\n \u2009=\u20090.94, long term:\n P<\/jats:italic>\n \u2009=\u20090.28) and risk of death (\n P<\/jats:italic>\n \u2009=\u20090.42) between the two groups.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions and relevance<\/jats:title>\n \n The presence of radiographic alveolar lesions and neutrophilia in BALF was significantly associated with the detection of\n M felis<\/jats:italic>\n in BALF. This association might be causal, consequential or contextual (ie, sharing the same cause). The detection of\n M felis<\/jats:italic>\n in BALF did not negatively impact prognosis but the necessity to treat\n M felis<\/jats:italic>\n using targeted antibiotics remains to be determined.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/1098612x241297870","type":"journal-article","created":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T06:49:57Z","timestamp":1735022997000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical and prognostic relevance of\n Mycoplasma felis<\/i>\n PCR detection in feline lower respiratory tract disease"],"prefix":"10.1177","volume":"26","author":[{"given":"Thibaud","family":"Robin","sequence":"first","affiliation":[{"name":"Centre Hospitalier V\u00e9t\u00e9rinaire Fregis \u2013 IVC Evidensia France, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Bigay","sequence":"additional","affiliation":[{"name":"Centre Hospitalier V\u00e9t\u00e9rinaire Fregis \u2013 IVC Evidensia France, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chlo\u00e9","family":"Touzet","sequence":"additional","affiliation":[{"name":"Clinique v\u00e9t\u00e9rinaire Olliolis, Ollioules, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8427-0520","authenticated-orcid":false,"given":"Kevin","family":"Le Boedec","sequence":"additional","affiliation":[{"name":"Centre Hospitalier V\u00e9t\u00e9rinaire Fregis \u2013 IVC Evidensia France, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,12,24]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00329"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2021.104893"},{"key":"e_1_3_2_4_2","first-page":"179","article-title":"Prevalence of Mycoplasma pneumoniae infection in pediatric patients with acute asthma exacerbation.","volume":"116","author":"Kassisse E","year":"2018","unstructured":"Kassisse E, Garc\u00eda H, Prada L, et al. 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Can Vet J 2013; 54: 132\u2013138.","journal-title":"Can Vet J"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-015-0595-2"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.1993.54.06.897"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X14524969"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.250.4.397"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/vcp.13000"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy419"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-023-08166-3"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2009.00767.x"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-005-0026-z"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2003.11.006"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2023.1148849"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/iid3.849"},{"key":"e_1_3_2_21_2","article-title":"Immune response plays a role in Mycoplasma pneumoniae pneumonia.","volume":"14","author":"Zhu Y","year":"2023","unstructured":"Zhu Y, Luo Y, Li L, et al. 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