{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T13:55:23Z","timestamp":1777470923129,"version":"3.51.4"},"reference-count":57,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2018,4,29]],"date-time":"2018-04-29T00:00:00Z","timestamp":1524960000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000056","name":"National Institute of Nursing Research","doi-asserted-by":"crossref","award":["T32NR014833"],"award-info":[{"award-number":["T32NR014833"]}],"id":[{"id":"10.13039\/100000056","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Biological Research For Nursing"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:p>\n                    Cardiopulmonary rehabilitation (CR) improves physical function and quality of life (QoL) in chronic obstructive pulmonary disease (COPD) and heart failure (HF), but it is unknown if CR improves outcomes in very severe disease. This study\u2019s purpose was to describe functional capacity (6-min walk distance [6MWD], steps\/day), symptoms (dyspnea, depression), QoL (Short-Form Health Survey\u2013Veterans [SF-36 V]) and cardiopulmonary function ( N-terminal pro-brain natriuretic peptide [NT-proBNP], forced expiratory volume in 1 s [FEV\n                    <jats:sub>1<\/jats:sub>\n                    ]), and derive predictors of mortality among patients with severe COPD and HF who participated in CR.\n                  <\/jats:p>\n                  <jats:sec>\n                    <jats:title>Methods and Results:<\/jats:title>\n                    <jats:p>\n                      In this secondary analysis of a randomized controlled trial comparing two CR methods in severe COPD and HF, 90 (COPD = 63, HF = 27) male veterans, mean age 66 \u00b1 9.24 years, 79% Caucasian, and body mass index 31 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      , were followed for 12 months after CR. The COPD group had greater functional decline than the HF group (6MWD, p = .006). Dyspnea was lower ( p = .001) and QoL higher ( p = .006) in the HF group. Mean NT-proBNP was higher in the HF group at all time points. FEV\n                      <jats:sub>1<\/jats:sub>\n                      improved over 12 months in both groups ( p = .01). Mortality was 8.9%, 16.7%, and 37.8% at 12, 24, and 60 months, respectively. One-year predictors of mortality were baseline total steps (&lt;3,000\/day), 6MWD (&lt;229 meters), and NT-proBNP level (&gt;2,000 mg\/pg).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In very severe COPD and HF, risks of mortality over 12 months can predict patients unlikely to benefit from CR and should be considered at initial referral.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1099800418772346","type":"journal-article","created":{"date-parts":[[2018,4,30]],"date-time":"2018-04-30T00:26:24Z","timestamp":1525047984000},"page":"429-439","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Mortality in Advanced Chronic Obstructive Pulmonary Disease and Heart Failure Following Cardiopulmonary Rehabilitation"],"prefix":"10.1177","volume":"20","author":[{"given":"Youjeong","family":"Kang","sequence":"first","affiliation":[{"name":"University of Utah School of Nursing, Salt Lake City, UT, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bonnie G.","family":"Steele","sequence":"additional","affiliation":[{"name":"Health Services Research and Development, VA Puget Sound Health Care System, Seattle, WA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert L.","family":"Burr","sequence":"additional","affiliation":[{"name":"Biobehavioral Nursing and Health Informatics, University of Washington School of Nursing, Seattle, WA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia M.","family":"Dougherty","sequence":"additional","affiliation":[{"name":"Health Services Research and Development, VA Puget Sound Health Care System, Seattle, WA, USA"},{"name":"Biobehavioral Nursing and Health Informatics, University of Washington School of Nursing, Seattle, WA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,4,29]]},"reference":[{"key":"bibr1-1099800418772346","unstructured":"American Heart Association. (2016). What is heart failure? Retrieved from http:\/\/www.heart.org\/HEARTORG\/Conditions\/HeartFailure\/AboutHeartFailure\/About-Heart-Failure_UCM_002044_Article.jsp#.V0VC6fkrJpg"},{"key":"bibr2-1099800418772346","unstructured":"American Lung Association. (2016). Chronic obstructive pulmonary disease (COPD). Retrieved from http:\/\/www.lung.org\/lung-health-and-diseases\/lung-disease-lookup\/copd\/"},{"key":"bibr3-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1007\/BF03337759"},{"key":"bibr4-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.11.020"},{"key":"bibr5-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0000000000000260"},{"key":"bibr6-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1378\/chest.119.1.77"},{"key":"bibr7-1099800418772346","first-page":"429","volume":"3","author":"Carson P. E.","year":"2015","journal-title":"Journal of the American College of Cardiology. Heart Failure"},{"key":"bibr8-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2006.00997.x"},{"key":"bibr9-1099800418772346","unstructured":"Cavill N., Kahlmeier S., Racioppi F. (Eds.). (2006). Physical activity and health in Europe: Evidence for action. Copenhagen, Denmark: World Health Organization. Retrieved from http:\/\/www.euro.who.int\/document\/e89490.pdf"},{"key":"bibr10-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.112.000291"},{"key":"bibr11-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"bibr12-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/280187"},{"key":"bibr13-1099800418772346","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2016.25.7.360"},{"key":"bibr14-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201408-365OC"},{"key":"bibr15-1099800418772346","doi-asserted-by":"crossref","first-page":"e0141274","DOI":"10.1371\/journal.pone.0141274","volume":"10","author":"Dwyer T.","year":"2015","journal-title":"PLOS One"},{"key":"bibr16-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.113.001420"},{"key":"bibr17-1099800418772346","doi-asserted-by":"crossref","first-page":"e14","DOI":"10.3909\/ricm0595","volume":"13","author":"Fonarow G. C.","year":"2012","journal-title":"Reviews in Cardiovascular Medicine"},{"key":"bibr18-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2012.12.014"},{"key":"bibr19-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.03.056"},{"key":"bibr20-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201603-0602OC"},{"key":"bibr21-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2003.11.035"},{"key":"bibr22-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2010.0479"},{"key":"bibr23-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1378\/chest.130.4.1220"},{"key":"bibr24-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfn029"},{"key":"bibr25-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.6.626"},{"key":"bibr26-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2015.04.006"},{"key":"bibr27-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1097\/HCR.0000000000000080"},{"key":"bibr28-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1183\/20734735.021114"},{"key":"bibr29-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1177\/1479972316642363"},{"key":"bibr30-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200510-1677OC"},{"key":"bibr31-1099800418772346","first-page":"CD003793","volume":"23","author":"McCarthy B.","year":"2015","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"bibr32-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2012.04.010"},{"key":"bibr33-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034505"},{"key":"bibr34-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1891\/1061-3749.19.2.76"},{"key":"bibr35-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1177\/2048872616649757"},{"key":"bibr36-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.111.963462"},{"key":"bibr37-1099800418772346","first-page":"w13777","volume":"143","author":"Osthoff M.","year":"2013","journal-title":"Swiss Medical Weekly"},{"key":"bibr38-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2007.12.001"},{"key":"bibr39-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2008.01.004"},{"key":"bibr40-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201209-1596OC"},{"key":"bibr41-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-6-54"},{"key":"bibr42-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.11.052"},{"key":"bibr43-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2007.01.010"},{"key":"bibr44-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2014-000163"},{"key":"bibr45-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-015-0319-y"},{"key":"bibr46-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.1.81"},{"key":"bibr47-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2007.11.003"},{"key":"bibr48-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1097\/rnj.0000000000000115"},{"key":"bibr49-1099800418772346","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S62563"},{"key":"bibr50-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-010106"},{"key":"bibr51-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1242637"},{"key":"bibr52-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2016.06.007"},{"key":"bibr53-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-1-13"},{"key":"bibr54-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00975-2015"},{"key":"bibr55-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201501-0081OC"},{"key":"bibr56-1099800418772346","first-page":"956","volume":"52","author":"Watson L. C.","year":"2003","journal-title":"Journal of Family Practice"},{"key":"bibr57-1099800418772346","doi-asserted-by":"publisher","DOI":"10.1378\/chest.15-0529"}],"container-title":["Biological Research For Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1099800418772346","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1099800418772346","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1099800418772346","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:40:45Z","timestamp":1777383645000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1099800418772346"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,29]]},"references-count":57,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1177\/1099800418772346"],"URL":"https:\/\/doi.org\/10.1177\/1099800418772346","relation":{},"ISSN":["1099-8004","1552-4175"],"issn-type":[{"value":"1099-8004","type":"print"},{"value":"1552-4175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,29]]}}}