{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T23:39:37Z","timestamp":1779147577558,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2001,4,1]],"date-time":"2001-04-01T00:00:00Z","timestamp":986083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2001,4]]},"abstract":"\n Purpose<\/jats:title>\n To clarify the usefulness of multilayer amniotic membrane transplantation in an unusual case of calcareous corneal degeneration in a patient with graft-versus-host disease.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A 20-year-old Caucasian woman had bilateral calcareous corneal degeneration of one year of evolution, secondary to graft-versus-host disease. Treatment for both eyes with topical steroids and antibiotic ointment was not successful. Right eye had a spontaneous corneal perforation, and a three-layer circle amniotic membrane graft was applied to the whole cornea.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n During a follow-up period of 20 months we observed stability of the corneal epithelium and stroma. The amniotic membrane-covered area showed rapid epithelization, reduced inflammation and suppressed fibrosis formation.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Multilayer amniotic membrane transplantation may be considered an alterantive for reconstructing the ocular surface in a patient with severe dry eyes and calcareous corneal degeneration, even with little perforation.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/112067210101100215","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:31:56Z","timestamp":1516321916000},"page":"183-186","source":"Crossref","is-referenced-by-count":46,"title":["Multilayer Amniotic Membrane Transplantation in Severe Ocular Graft versus Host Disease"],"prefix":"10.1177","volume":"11","author":[{"given":"C.","family":"Peris-Mart\u00ednez","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University Hospital \u201cLa Fe\u201d, Valencia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.L.","family":"Menezo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital \u201cLa Fe\u201d, Valencia"},{"name":"Department of Surgery, University of Valencia, Valencia"},{"name":"Fundaci\u00f3n Oftalmol\u00f3gica del Mediterr\u00e1neo, Valencia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"D\u00edaz-Llopis","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital \u201cLa Fe\u201d, Valencia"},{"name":"Department of Surgery, University of the Basque Country, Basque Country - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.A.","family":"Avi\u00f1\u00f3-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital \u201cLa Fe\u201d, Valencia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Navea-Tejerina","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital \u201cLa Fe\u201d, Valencia"},{"name":"Department of Surgery, University of Valencia, Valencia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Risue\u00f1o-Reguillo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital \u201cLa Fe\u201d, Valencia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2001,4,1]]},"reference":[{"key":"bibr1-112067210101100215","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(80)90380-0"},{"key":"bibr2-112067210101100215","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(83)34604-2"},{"key":"bibr3-112067210101100215","doi-asserted-by":"publisher","DOI":"10.1016\/0039-6257(89)90129-X"},{"key":"bibr4-112067210101100215","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199509000-00006"},{"key":"bibr5-112067210101100215","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)71962-2"},{"key":"bibr6-112067210101100215","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)70125-4"},{"key":"bibr7-112067210101100215","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)71693-9"},{"key":"bibr8-112067210101100215","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.116.4.431"},{"key":"bibr9-112067210101100215","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(97)30057-8"},{"key":"bibr10-112067210101100215","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90444-X"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067210101100215","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067210101100215","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:38:33Z","timestamp":1777405113000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/112067210101100215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,4]]}},"alternative-id":["10.1177\/112067210101100215"],"URL":"https:\/\/doi.org\/10.1177\/112067210101100215","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,4]]}}}