{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T22:05:30Z","timestamp":1778277930557,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2001,10,1]],"date-time":"2001-10-01T00:00:00Z","timestamp":1001894400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2001,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Regulation of ocular blood flow might be impaired in glaucoma patients. We compared the reaction of retinal vessels to a short-term increase of intraocular pressure (IOP), using a retinal vessel analyzer (RVA), in normal volunteers, ocular hypertensive patients (OH) and primary open angle glaucoma patients (POAG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Ten healthy subjects (56 \u00b1 8 years, IOP 13.7 \u00b1 1.6 mmHg), 10 OH patients (55 \u00b1 12 years, IOD 23.4 \u00b1 4.1 mmHg) and 11 POAG patients (60 \u00b1 11 years, IOP 23.3 \u00b1 1.95 mmHg) were evaluated. Arterial and venous retinal vessel diameter was measured continuously before, during and after raising IOP to suprasystolic values by the suction cup method, described as ocular oscillo-dynamography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The change in vessel diameter after the IOP rise differed in its temporal sequence and in absolute values depending on the group examined. In the retinal branch veins the reduction of vessel diameter during the IOP rise was significantly different in POAG (0% \u00b1 6.7) and volunteers (-6.7% \u00b1 8.5; p = 0.06) and in POAG and OH (-6.7% \u00b1 7.0; p = 0.04). At 70\u2013130 sec after IOP increase a dilatation occurred, again differing significantly in POAG (+5.8% \u00b1 3.9) and volunteers (+9.7% \u00b1 4.3; p = 0.03). Systemic blood pressure did not show any significant differences between groups or during the course of the examination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>At short-term rise in IOP leads to less retinal vessel reaction in POAG patients than in volunteers and OH. This might be due to impaired autoregulation to ocular perfusion changes in POAG patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/112067210101100404","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:29:49Z","timestamp":1516321789000},"page":"338-344","source":"Crossref","is-referenced-by-count":42,"title":["Retinal Vessel Reaction to Short-Term IOP Elevation in Ocular Hypertensive and Glaucoma Patients"],"prefix":"10.1177","volume":"11","author":[{"given":"E.","family":"Nagel","sequence":"first","affiliation":[{"name":"Ophthalmic private practice, Rudolstadt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Vilser","sequence":"additional","affiliation":[{"name":"Technical University, Ilmenau"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.M.","family":"Lanzi","sequence":"additional","affiliation":[{"name":"Eye Department of the Technical University, Munich - 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