{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:13:48Z","timestamp":1777580028211,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2003,6,1]],"date-time":"2003-06-01T00:00:00Z","timestamp":1054425600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2003,6]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To describe the occurrence of atypical, bilateral detachment of the macular neuroepithelium and Klinefelter syndrome in a young patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Case report.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A 20-year-old male of Chinese origin with karyotype 47,XXY presented with bilateral central neurosensory retinal detachment. There was spontaneous improvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>An atypical form of detachment of the macular neuroepithelium was seen in a young patient with Klinefelter syndrome. The pathophysiological mechanism is not clear. The possibility of a hormonal imbalance is discussed. A differential diagnostic consideration is central serous chorioretinopathy and a mild form of Vogt-Koyanagi-Harada syndrome. This case is of interest because of the rarity of association between Klinefelter syndrome and chorioretinal abnormalities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/112067210301300511","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:37:26Z","timestamp":1516322246000},"page":"486-490","source":"Crossref","is-referenced-by-count":1,"title":["Bilateral Detachment of the Macular Neuroepithelium in a Patient with Klinefelter Syndrome"],"prefix":"10.1177","volume":"13","author":[{"given":"J.","family":"Van Haarlem","sequence":"first","affiliation":[{"name":"Institute of Ophthalmology, University Medical Centre Nijmegen, Nijmegen - The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.R.M.","family":"Cruysberg","sequence":"additional","affiliation":[{"name":"Institute of Ophthalmology, University Medical Centre Nijmegen, Nijmegen - The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.F.","family":"Deutman","sequence":"additional","affiliation":[{"name":"Institute of Ophthalmology, University Medical Centre Nijmegen, Nijmegen - The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2003,6,1]]},"reference":[{"key":"bibr1-112067210301300511","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-2-11-615"},{"key":"bibr2-112067210301300511","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-16-5-689"},{"key":"bibr3-112067210301300511","unstructured":"BehrmannR.E.KliegmannR.M.JensonH.B. 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