{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:57:33Z","timestamp":1777579053617,"version":"3.51.4"},"reference-count":51,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Pseudoexfoliation syndrome (PES) seems to be a systemic condition. However, to an ophthalmologist it represents a continual challenge, due to unclear etiology and pathogenesis, and because of a potential for development of an aggressive glaucoma, and cataract surgery complications. According to some findings, PES could be a factor of hastened aging, which means that it could be considered as a secondary aging factor.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Frequencies of secondary aging diseases (non-insulin dependent diabetes mellitus, atherosclerotic myocardiopathy chronic obstructive lung diseases, arterial hypertension, and PES) were investigated in 162 patients with age-related cataract and 55 age- and sex-matched control subjects, and analyzed by a logistic regression. The authors also determined elements of antioxidative protection in a group of sera from patients with cataract and PES, and compared them to those obtained from patients with cataract without PES (activity of catalase and peroxidase, glutathione, vitamins C and E), and total antioxidative protection (%iMDA). Antioxidant defense of aqueous humors, expressed as a rate of induced malondialdehyde (%iMDA), and total thiol groups in the lens corticonuclear blocks (TSH) were estimated in samples of 17 patients with PES and cataract and 55 patients with cataract only.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Logistic regression showed the highest odds ratio for PES (OR=4.516; p&lt;0.05). Catalytic activity of serum catalase had significantly lower values in patients with PES (p&lt;0.05). Antioxidative defense of aqueous humor and lens had lower values in patients with PES.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results indicate that PES might be a significant factor for cataractogenesis. At least a part of pathogenesis alterations in an eye with PES could be the result of higher intensity of oxidative stress.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/112067210601600212","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:48:42Z","timestamp":1516322922000},"page":"268-273","source":"Crossref","is-referenced-by-count":18,"title":["Pseudoexfoliation Syndrome and its Antioxidative Protection Deficiency as Risk Factors for Age-Related Cataract"],"prefix":"10.1177","volume":"16","author":[{"given":"L.","family":"Zoric","sequence":"first","affiliation":[{"name":"Clinic for Eye Diseases, Faculty of Medicine, University of Pristina, settlement Kosovska Mitrovica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Miric","sequence":"additional","affiliation":[{"name":"Institute for Biochemistry, Faculty of Medicine, University of Pristina, settlement Kosovska Mitrovica"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Milenkovic","sequence":"additional","affiliation":[{"name":"Institute for Eye Diseases, Faculty of Medicine, Belgrade University, Belgrade"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Jovanovic","sequence":"additional","affiliation":[{"name":"Clinic for Eye Diseases, Faculty of Medicine, Univeristy in Nis, Nis"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Trajkovic","sequence":"additional","affiliation":[{"name":"Institute for Medical Statistics, Faculty of Medicine, University of Pristina, settlement Kosovska Mitrovica - Serbia and Montenegro"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,3,1]]},"reference":[{"key":"bibr1-112067210601600212","first-page":"447","volume-title":"Harrison's Principles of Internal Medicine.","author":"Hazzard W.R.","year":"1987"},{"key":"bibr2-112067210601600212","doi-asserted-by":"publisher","DOI":"10.1016\/1047-2797(95)00094-1"},{"key":"bibr3-112067210601600212","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1994.01090150027002"},{"key":"bibr4-112067210601600212","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(98)96020-1"},{"key":"bibr5-112067210601600212","first-page":"1400","volume-title":"Albert & Jakobiec Principles and Practice of Ophthalmology","volume":"3","author":"Johnson D.H.","year":"1994"},{"key":"bibr6-112067210601600212","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022949121078"},{"key":"bibr7-112067210601600212","first-page":"394","volume":"8","author":"Ringvold A.","year":"1972","journal-title":"Acta Ophthalmol"},{"key":"bibr8-112067210601600212","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/j.1755-3768.1973.tb06018.x","volume":"52","author":"Ringvold A.","year":"1973","journal-title":"Acta Ophthalmol (Copenh)"},{"key":"bibr9-112067210601600212","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1992.01080240092038"},{"key":"bibr10-112067210601600212","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1992.01080240097039"},{"key":"bibr11-112067210601600212","doi-asserted-by":"publisher","DOI":"10.1016\/S1350-9462(00)00018-5"},{"key":"bibr12-112067210601600212","doi-asserted-by":"publisher","DOI":"10.1076\/ceyr.28.1.5.23490"},{"key":"bibr13-112067210601600212","doi-asserted-by":"publisher","DOI":"10.1076\/ceyr.22.2.154.5522"},{"key":"bibr14-112067210601600212","first-page":"168","author":"Zoric L.","year":"1998","journal-title":"Program and abstract book."},{"key":"bibr15-112067210601600212","first-page":"927","volume-title":"Textbook of Clinical Chemistry.","author":"McCorwick D.B.","year":"1986"},{"key":"bibr16-112067210601600212","volume-title":"Medical Biochemistry.","author":"Straus B.","year":"1988"},{"key":"bibr17-112067210601600212","first-page":"168","volume-title":"Practical Hematology.","author":"Dacie J.V.","year":"1985"},{"key":"bibr18-112067210601600212","first-page":"16","volume":"1","author":"Koroljuk M.A.","year":"1988","journal-title":"Lab Delo"},{"key":"bibr19-112067210601600212","unstructured":"Majkic SinghN. 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