{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:00:54Z","timestamp":1777579254157,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To compare the efficacy, safety, and local tolerance between carbomer-based artificial tears, cellulose-, and mineral oil-based artificial tears.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A randomized, open-label, parallel-group comparative 28-day study was designed for 67 patients who were randomized into three treatment groups. Measurements included the scoring of total subjective symptoms and objective signs, Schirmer-Jones test values, and tear break-up time (BUT) at baseline, and after 2 and 4 weeks of treatment. Safety of study treatment was also assessed. Outcomes measured at baseline and 2 and 4 weeks follow-up included the scoring of total subjective symptoms and objective signs, Schirmer-Jones test values, and tear BUT, subjective assessments, and safety.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were no differences regarding total scores, Schirmer-Jones test, or tear BUT at baseline among these three groups at 2 and 4 weeks. Patients in all three treatment groups experienced a significant improvement from baseline in total scores and Schirmer-Jones test values after treatment. Subjective assessment was better with carbomer-based treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Each artificial tear formulation successfully relieved symptoms and signs of keratoconjunctivitis sicca. The tolerance of carbomer-based artificial tears was comparable to that of cellulose- and mineral oil-based artificial tears. (Eur J Ophthalmol 2007; 17: 151\u20139)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/112067210701700202","type":"journal-article","created":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T11:13:57Z","timestamp":1516792437000},"page":"151-159","source":"Crossref","is-referenced-by-count":14,"title":["A Comparison of the Effect of Carbomer-, Cellulose-, and Mineral Oil-Based Artificial Tear Formulations"],"prefix":"10.1177","volume":"17","author":[{"given":"I.-J.","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei - Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.-C.","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei - Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.-C.","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei - Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.-R.","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei - Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2007,3,1]]},"reference":[{"key":"bibr1-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4615-5359-5_111"},{"key":"bibr2-112067210701700202","first-page":"215","volume":"10","author":"Dohlman C.H.","year":"1970","journal-title":"Int Ophthalmol Clin"},{"key":"bibr3-112067210701700202","first-page":"116","volume":"4","author":"Bach F.C.","year":"1972","journal-title":"Ann Ophthalmol"},{"key":"bibr4-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1097\/00004397-198002030-00016"},{"key":"bibr5-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(84)34173-2"},{"key":"bibr6-112067210701700202","first-page":"649","volume":"69","author":"Swanson M.","year":"1998","journal-title":"J Am Optom Assoc"},{"key":"bibr7-112067210701700202","first-page":"221","volume":"21","author":"Lemp M.A.","year":"1995","journal-title":"CLAO J"},{"key":"bibr8-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(66)91676-X"},{"key":"bibr9-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1177\/112067210501500602"},{"key":"bibr10-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1191\/1740774505cn119oa"},{"key":"bibr11-112067210701700202","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0889-857X(21)00318-5","volume":"18","author":"Friedlaender M.H.","year":"1992","journal-title":"Rheum Dis Clin North Am"},{"key":"bibr12-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1988.01060130530029"},{"key":"bibr13-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(97)30124-9"},{"key":"bibr14-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1050799"},{"key":"bibr15-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.1996.tb00086.x"},{"key":"bibr16-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.1997.tb00413.x"},{"key":"bibr17-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199603000-00003"},{"key":"bibr18-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199807000-00015"},{"key":"bibr19-112067210701700202","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1002543"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067210701700202","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067210701700202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:37:06Z","timestamp":1777405026000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/112067210701700202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["10.1177\/112067210701700202"],"URL":"https:\/\/doi.org\/10.1177\/112067210701700202","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}