{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:03:17Z","timestamp":1777579397460,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      To compare the efficacy of 2.5% sodium hyaluronate (BD Multivisc\n                      <jats:sup>\u2122<\/jats:sup>\n                      ) with the soft shell technique in reducing corneal endothelial cell damage during cataract phacoemulsification in patients with hard lens nucleus (3+) and cornea guttata.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Thirty patients (37 eyes) scheduled for cataract surgery at Department of Ophthalmology and Visual Sciences, University Hospital San Raffaele, Milano, Italy. Thirty-seven eyes (randomly divided into Groups A and B) with hard lens nucleus (grade 3 or higher) and cornea guttata had phacoemulsification using the soft shell technique (Group A) with Biolon\n                      <jats:sup>\u00ae<\/jats:sup>\n                      (sodium hyaluronate 1%) and Viscoat\n                      <jats:sup>\u00ae<\/jats:sup>\n                      (sodium hyaluronate 3%-chondroitin sulfate 4%) or with BD Multivisc\n                      <jats:sup>\u2122<\/jats:sup>\n                      alone (Group B). Patients were evaluated preoperatively and after 1, 15, 90, and 180 days, checked for best-corrected visual acuity (BCVA), intraocular pressure (IOP), central corneal thickness, and corneal endothelial density. Stop and chop phacoemulsification technique, with burst mode (Alcon Legacy 20000, Advantec), was performed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were no significant differences between the two groups at 3 and 6 months in BCVA, IOP, corneal thickness, or endothelial cell density. The increase of central corneal thickness (preoperative: Group A 584\u00b130 \u03bcm, Group B 573\u00b130 \u03bcm; postoperative at 90 days: Group A 593\u00b138 \u03bcm, Group B 577\u00b125 \u03bcm) was not significant. Endothelial cell loss was similar in both groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The results suggest that the soft shell technique (Biolon\n                      <jats:sup>\u00ae<\/jats:sup>\n                      , Viscoat\n                      <jats:sup>\u00ae<\/jats:sup>\n                      ) and 2.5% sodium hyaluronate (BD Multivisc\n                      <jats:sup>\u2122<\/jats:sup>\n                      ) are both effective in protecting the corneal endothelium in Fuchs dystrophy during phacoemulsification in patients with hard lens nucleus.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/112067210701700504","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:47:04Z","timestamp":1516322824000},"page":"709-713","source":"Crossref","is-referenced-by-count":9,"title":["Comparison of BD Multivisc\n                    <sup>\u2122<\/sup>\n                    with the Soft Shell Technique in Cases with Hard Lens Nucleus and Fuchs Endothelial Dystrophy"],"prefix":"10.1177","volume":"17","author":[{"given":"F.","family":"Fasce","sequence":"first","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Spinelli","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Bolognesi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Rossi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Gemma","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, University Hospital San Raffaele, Milano - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2007,7,1]]},"reference":[{"key":"bibr1-112067210701700504","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2003.031948"},{"key":"bibr2-112067210701700504","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000121708.58571.5b"},{"key":"bibr3-112067210701700504","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(80)35185-3"},{"key":"bibr4-112067210701700504","first-page":"98","volume":"13","author":"Arshinoff S.A.","year":"1995","journal-title":"Ophthalmic Pract"},{"key":"bibr5-112067210701700504","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(99)80121-7"},{"key":"bibr6-112067210701700504","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(02)01323-8"},{"key":"bibr7-112067210701700504","first-page":"332","volume":"17","author":"Arshinoff S.A.","year":"1999","journal-title":"Ophthalmic Pract"},{"key":"bibr8-112067210701700504","first-page":"45","volume-title":"Surgical Technique, Complications and Results.","author":"Emery J.M.","year":"1979"},{"key":"bibr9-112067210701700504","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(99)00420-4"},{"key":"bibr10-112067210701700504","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-5155(00)00295-1"},{"key":"bibr11-112067210701700504","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200011000-00010"},{"key":"bibr12-112067210701700504","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199711000-00004"},{"key":"bibr13-112067210701700504","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(00)00568-X"},{"key":"bibr14-112067210701700504","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(99)00367-3"},{"key":"bibr15-112067210701700504","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2003.09.045"},{"key":"bibr16-112067210701700504","first-page":"441","volume":"112","author":"Seitzmann G.D.","year":"2005","journal-title":"J Cataract Refract Surg"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067210701700504","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067210701700504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:37:27Z","timestamp":1777405047000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/112067210701700504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["10.1177\/112067210701700504"],"URL":"https:\/\/doi.org\/10.1177\/112067210701700504","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7]]}}}