{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:05:36Z","timestamp":1777579536602,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To report the unknown coexistence of bilateral optic disc pit and keratoconus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 23-year-old man with bilateral keratoconus underwent complete ophthalmology screening, with an unexpected detection of undiagnosed optic disc pit in both eyes. Computerized corneal topography (CT), Orbscan, corneal pachometry, endothelial microscopy, and optical coherence tomography (OCT) examination were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The corneal CT showed a keratoconus pattern in both eyes, evolved in the right eye with a minimum corneal pachometry of 336 \u03bcm in the right eye and 405 \u03bcm in the left eye. Mean endothelial cell density was 1937 cells\/mm\n                      <jats:sup>2<\/jats:sup>\n                      in the right eye and 1912 cells\/mm\n                      <jats:sup>2<\/jats:sup>\n                      in the left eye. The OCT scans showed the presence of the disc pit in both eyes with a normal macular thickness and profile in the right eye, and in the left eye an augmented retinal thickness in the nasal macular zone due to retinal oedema and schisis, with an initial detachment of the neuroepithelium in the parapapillary area starting from the optic pit.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This is the first clinical report of bilateral optic disc pit and keratoconus. Further investigations will be necessary to assess if there is a possible pathogenetic correlation between these two ocular pathologies or if this is an unusual coexistence of separate entities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/112067210801800124","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:49:40Z","timestamp":1516322980000},"page":"134-137","source":"Crossref","is-referenced-by-count":7,"title":["Unusual Coexistence of Bilateral Keratoconus and Optic Disc Pit: A Case Report"],"prefix":"10.1177","volume":"18","author":[{"given":"R.","family":"Fasciani","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Catholic University of Sacro Cuore, Agostino Gemelli Polyclinic, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Mosca","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Catholic University of Sacro Cuore, Agostino Gemelli Polyclinic, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.I.","family":"Giannico","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Catholic University of Sacro Cuore, Agostino Gemelli Polyclinic, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.F.","family":"Legrottaglie","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Catholic University of Sacro Cuore, Agostino Gemelli Polyclinic, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Balestrazzi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Catholic University of Sacro Cuore, Agostino Gemelli Polyclinic, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,1,18]]},"reference":[{"key":"bibr1-112067210801800124","doi-asserted-by":"publisher","DOI":"10.1007\/BF00159993"},{"key":"bibr2-112067210801800124","first-page":"144","volume":"15","author":"Brown G.C.","year":"1980","journal-title":"Can J Ophthalmol"},{"key":"bibr3-112067210801800124","doi-asserted-by":"publisher","DOI":"10.1097\/00004397-198402410-00009"},{"key":"bibr4-112067210801800124","doi-asserted-by":"crossref","unstructured":"Duke-Elder. 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