{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:06:26Z","timestamp":1777579586282,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2008,5,1]],"date-time":"2008-05-01T00:00:00Z","timestamp":1209600000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To describe and compare long-term (\u226536 months) effects of patients with 86 primary pterygia treated with bare sclera extirpation (BSE) followed by \u03b2-RT or by sham irradiation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospective, multicenter, randomized, double-blind study After BSE of their pterygium, patients were randomized to either \u03b2-RT or sham irradiation. In the case of \u03b2-RT, within 24 hours after the operation, a 90Sr eye applicator was used to deliver 2500 cGy to the sclera surface at a dose rate of between 200 and 250 cGy\/min. Sham irradiation was given using the same type of applicator without the 90Sr layer. After treatment, both a masked ophthalmologist and a radiation oncologist performed follow-up examinations. These were continued until either a relapse occurred or at least 36 months had elapsed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Adequate follow-up was available of 86 pterygia in 81 patients, treated between February 1998 and September 2002. Fifty-two (60%) patients were male. The mean age of the patients was 50 years (range: 24\u201377). After a follow-up of at least 36 months (mean: 40 months, SD:13.9 months), 5 out of 44 eyes (11%) treated with \u03b2-RT showed a recurrence versus 32 out of 42 eyes (76%) treated with sham-RT (after a mean follow-up of 22 months) (p&lt;0.001). In the \u03b2-RT group, 80% were satisfied with the cosmetic result, whereas in the sham group this percentage was 41% (p&lt;0.001). In the \u03b2-RT group, no scar or a white scar could be detected in 86% of the treated eyes, versus in 24% of the sham irradiated eyes (p&lt;0.001). A change of keratometry (Javal) was seen in 5 patients (12%) following \u03b2-RT compared to 16 (38%) after sham irradiation (p=0.002). Complications were few: a granuloma was seen in three patients after sham irradiation, mild limitation of abduction in two \u03b2-RT patients versus in five after sham irradiation, and mild scleromalacia in one \u03b2-RT patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Bare sclera extirpation of a pterygium without adjuvant treatment has an unacceptably high recurrence rate and therefore should be considered obsolete. Bare sclera extirpation of a primary pterygium followed by a single-dose \u03b2-RT is a simple, effective, and safe treatment with lasting results and very few complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/112067210801800301","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:51:56Z","timestamp":1516323116000},"page":"327-331","source":"Crossref","is-referenced-by-count":18,"title":["Favorable Long-Term Results of Primary Pterygium Removal by Bare Sclera Extirpation Followed by a Single\n                    <sup>90<\/sup>\n                    Strontium Application"],"prefix":"10.1177","volume":"18","author":[{"given":"M.P.","family":"Mourits","sequence":"first","affiliation":[{"name":"Department of Surgical Specialties, Division of Ophthalmology, University Medical Center Utrecht, Utrecht"},{"name":"Department of Ophthalmology, Academic Medical Center, Amsterdam - The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.K.","family":"Wyrdeman","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, University Medical Center Utrecht, Utrecht"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.M.","family":"J\u00fcrgenliemk-Schulz","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, University Medical Center Utrecht, Utrecht"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Bidlot","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Academic Medical Center, Amsterdam - The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,1,18]]},"reference":[{"key":"bibr1-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(89)32667-4"},{"key":"bibr2-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.82.6.661"},{"key":"bibr3-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.79.5.439"},{"key":"bibr4-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)72602-9"},{"key":"bibr5-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(95)30770-1"},{"key":"bibr6-112067210801800301","doi-asserted-by":"publisher","DOI":"10.3928\/1542-8877-19970801-09"},{"key":"bibr7-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006070503345"},{"key":"bibr8-112067210801800301","first-page":"289","volume":"4","author":"Castroviejo R.","year":"1952","journal-title":"L'Ann Th\u00e9rap Ophthalmol"},{"key":"bibr9-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-195907000-00001"},{"key":"bibr10-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2003.12.021"},{"key":"bibr11-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1993.01090070065021"},{"key":"bibr12-112067210801800301","first-page":"1476","volume":"90","author":"Luanratanakorn P.","year":"2006","journal-title":"J Ophthalmol"},{"key":"bibr13-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1997.01100160405001"},{"key":"bibr14-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(99)80235-9"},{"key":"bibr15-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2003.036830"},{"key":"bibr16-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(92)90687-D"},{"key":"bibr17-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(99)00419-8"},{"key":"bibr18-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(00)00701-X"},{"key":"bibr19-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1007\/s00066-006-1484-1"},{"key":"bibr20-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-199908000-00010"},{"key":"bibr21-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)01160-0"},{"key":"bibr22-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000164780.25914.0a"},{"key":"bibr23-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2004.08.028"},{"key":"bibr24-112067210801800301","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2004.08.022"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067210801800301","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067210801800301","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:37:54Z","timestamp":1777405074000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/112067210801800301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1177\/112067210801800301"],"URL":"https:\/\/doi.org\/10.1177\/112067210801800301","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5]]}}}