{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:42:22Z","timestamp":1783694542718,"version":"3.55.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the data of penetrating keratoplasty over a 10-year period and to compare indications and outcomes of eyes undergoing single graft with those of eyes requiring regrafting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 652 eyes of 613 patients required single graft (Group I). Sixty-one regrafts were performed on 53 eyes (Group II). The mean follow-up time was 23.4\u00b121.3 months (range 6\u2013132 months). The results were evaluated for the following criteria: primary indications, allograft reactions, graft clarity, final postoperative visual acuity, and complications leading to reduction in vision.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The most common indication was keratoconus (228 eyes; 35.0%) in Group I, and vascularized corneal scar (12 eyes; 22.6%) in Group II. Allograft reactions occurred in 96 eyes (14.7%) in Group I, and 17 eyes (32.0%) in Group II (p=0.001). At the end of the study period, 76.4% of patients in Group I had entirely clear grafts, whereas 45.3% of patients in Group II had entirely clear grafts (p=0.000). The main causes of corneal graft failure were irreversible allograft reaction, endothelial failure, and graft infection, which were all seen in higher percentage in the regraft group. A best-corrected visual acuity of 20\/100 or better was achieved in 377 eyes (57.8%) in Group I and 11 eyes (20.7%) in Group II (p=0.000).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The complications of repeated surgery may reduce final graft clarity and visual acuity; the disease process necessitating regrafting may carry a poorer prognosis for sight.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/112067210901900306","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:52:55Z","timestamp":1516323175000},"page":"362-368","source":"Crossref","is-referenced-by-count":29,"title":["Repeat Penetrating Keratoplasty: Indications and Prognosis, 1995\u20132005"],"prefix":"10.1177","volume":"19","author":[{"given":"Zuleyha","family":"Yalniz-Akkaya","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Ankara Training and Research Hospital, Ankara - Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse Burcu","family":"Nurozler","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Ankara Training and Research Hospital, Ankara - Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvin Hatice","family":"Yildiz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Ankara Training and Research Hospital, Ankara - Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Onat","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Ankara Training and Research Hospital, Ankara - Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koray","family":"Budak","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Ankara Training and Research Hospital, Ankara - Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunay","family":"Duman","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Ankara Training and Research Hospital, Ankara - Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,1,18]]},"reference":[{"key":"bibr1-112067210901900306","first-page":"361","volume":"81","author":"Arentsen J.J.","year":"1983","journal-title":"Trans Am Ophthalmol Soc"},{"key":"bibr2-112067210901900306","unstructured":"KratchmerJ.H., MannisM.J., HollandE.J. 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