{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:52:35Z","timestamp":1777578755491,"version":"3.51.4"},"reference-count":7,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose.<\/jats:title>\n                    <jats:p>To report on a patient with retinal astrocytic hamartoma, who developed a choroidal neovascularization (CNV), effectively treated by intravitreal ranibizumab injections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>A 74-year-old woman who, 12 years before, had been diagnosed with a yellow-gray lesion in the left eye (OS) presented in our department for OS decreased vision of recent onset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>Upon a complete ophthalmologic examination including ultrasonography, fluorescein angiography (FA), and spectral domain optical coherence tomography (SD-OCT), the patient was diagnosed with retinal astrocytic hamartoma and coincident CNV on its foveal border. Six months after 3 monthly intravitreal ranibizumab injections, FA and OCT revealed the CNV closure and absence of intraretinal and subretinal fluid on the foveal border of the retinal astrocytic hamartoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions.<\/jats:title>\n                    <jats:p>Associations between retinal astrocytic hamartoma and CNV have not been previously reported. Intravitreal ranibizumab injection appears an attractive therapeutic option for patients showing such an unusual association.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/112067211002000424","type":"journal-article","created":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T11:05:53Z","timestamp":1516791953000},"page":"789-791","source":"Crossref","is-referenced-by-count":8,"title":["Intravitreal Ranibizumab for Choroidal Neovascularization Associated with Retinal Astrocytic Hamartoma"],"prefix":"10.1177","volume":"20","author":[{"given":"Giuseppe","family":"Querques","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Hopital Intercommunal de Creteil, University Paris XII, Paris - France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Houda","family":"Kerrate","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hopital Intercommunal de Creteil, University Paris XII, Paris - France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Leveziel","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hopital Intercommunal de Creteil, University Paris XII, Paris - France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Coscas","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hopital Intercommunal de Creteil, University Paris XII, Paris - France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisele","family":"Soubrane","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hopital Intercommunal de Creteil, University Paris XII, Paris - France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric H.","family":"Souied","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hopital Intercommunal de Creteil, University Paris XII, Paris - France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,1,24]]},"reference":[{"key":"bibr1-112067211002000424","unstructured":"ShieldsJ.A., ShieldsC.L. Intraocular Tumors: A Text and Atlas. Philadelphia: WB Saunders; 1992: 421\u201336."},{"key":"bibr2-112067211002000424","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1976.03910040149003"},{"key":"bibr3-112067211002000424","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.03.032"},{"key":"bibr4-112067211002000424","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1999.3192"},{"key":"bibr5-112067211002000424","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa054481"},{"key":"bibr6-112067211002000424","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa062655"},{"key":"bibr7-112067211002000424","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(03)00540-3"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067211002000424","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067211002000424","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:35:28Z","timestamp":1777404928000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/112067211002000424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":7,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["10.1177\/112067211002000424"],"URL":"https:\/\/doi.org\/10.1177\/112067211002000424","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7]]}}}