{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T01:10:51Z","timestamp":1784941851633,"version":"3.55.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Debate exists in the literature on the prevalence and etiology of neovascularization following central retinal artery occlusion (CRAO). The reported prevalence varies from 2.5% to 31.6%. We conducted a retrospective study to determine the prevalence of ocular neovascularization following acute CRAO in our institution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective audit of consecutive patients with nonarteritic\/thromboembolic CRAO presenting between 1997 and 2009 in a single tertiary teaching hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty-three patients were identified as having nonarteritic CRAO, and of this cohort 6 patients (18.2%) developed ocular neovascularization. Neovascular glaucoma was present in 5 cases (15.2%); 2 of these presented through an emergency department with painful eyes, both at 16 weeks post CRAO. The other cases of neovascularization were detected on scheduled follow-ups. Mean time from retinal occlusive event to observed neovascularization was 8.5 weeks (range 2\u201316 weeks). One case of neovascularization was associated with hemodynamically significant ipsilateral carotid stenosis; no patient had proliferative diabetic retinopathy or other causes of neovascularization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The prevalence of neovascularization following acute CRAO in our population was 18.2% at an average of 8.5 weeks post CRAO. There was a temporal relationship between the 2 events and no other causes of neovascularization demonstrable in our cohort of patients. There is no consensus on the follow-up regimen post CRAO to detect ocular neovascularization complications. Our study suggests that neovascularization can occur early and regular follow-up especially in the first 4 months is important post CRAO.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/112067211002000603","type":"journal-article","created":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T11:03:13Z","timestamp":1516791793000},"page":"1042-1046","source":"Crossref","is-referenced-by-count":61,"title":["Ocular Neovascularization following Central Retinal Artery Occlusion: Prevalence and Timing of Onset"],"prefix":"10.1177","volume":"20","author":[{"given":"Adam K.","family":"Rudkin","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, NH&MRC Centre of Clinical Eye Research, Flinders Medical Centre and Flinders University, Adelaide, South Australia - Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew W.","family":"Lee","sequence":"additional","affiliation":[{"name":"Flinders Comprehensive Stroke Centre, Flinders University, Adelaide - Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celia S.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, NH&MRC Centre of Clinical Eye Research, Flinders Medical Centre and Flinders University, Adelaide, South Australia - Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,1,24]]},"reference":[{"key":"bibr1-112067211002000603","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(98)00035-6"},{"key":"bibr2-112067211002000603","doi-asserted-by":"publisher","DOI":"10.1080\/08820530902800801"},{"key":"bibr3-112067211002000603","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.78.4.260"},{"key":"bibr4-112067211002000603","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2005.029744"},{"key":"bibr5-112067211002000603","doi-asserted-by":"publisher","DOI":"10.3341\/kjo.2009.23.3.215"},{"key":"bibr6-112067211002000603","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1001\/archopht.120.9.1234","volume":"120","author":"Kattah J.C.","year":"2002","journal-title":"Arch Ophthalmol"},{"key":"bibr7-112067211002000603","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.03.006"},{"key":"bibr8-112067211002000603","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1982.01030040563002"},{"key":"bibr9-112067211002000603","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1991.01080030041034"},{"key":"bibr10-112067211002000603","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199108153250701"},{"key":"bibr11-112067211002000603","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2009.142"},{"key":"bibr12-112067211002000603","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(88)33042-3"},{"key":"bibr13-112067211002000603","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1055\/s-2005-858076","volume":"222","author":"Sch\u00e4fer S.","year":"2005","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"bibr14-112067211002000603","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1997.01100150488006"},{"key":"bibr15-112067211002000603","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(89)32947-2"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067211002000603","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/112067211002000603","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:35:37Z","timestamp":1777404937000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/112067211002000603"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["10.1177\/112067211002000603"],"URL":"https:\/\/doi.org\/10.1177\/112067211002000603","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11]]}}}