{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:27:30Z","timestamp":1777580850896,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2018,3,23]],"date-time":"2018-03-23T00:00:00Z","timestamp":1521763200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To assess the effectiveness of autologous platelet-rich plasma for the treatment of dormant corneal ulcers secondary to corneal surgery and unresponsive to conventional treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>VISSUM, Ophthalmology Institute of Alicante, Alicante, Spain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Prospective nonrandomized, observational consecutive study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A total of 44 eyes of 28 patients with dormant corneal ulcers secondary to corneal surgery were included in a prospective study and treated with autologous platelet-rich plasma during 6 weeks. Wilcoxon signed-rank test was used to compare the effect of the treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In all, 28 patients (65.1%) improved their visual acuity at least one line in Snellen chart, 26 (59.09%) had a decrease in the size of the ulcer or even a total closure, and 40 (90.9%) experienced an improvement in their symptoms. The results are also provided for the four groups of patients (keratoplasty, refractive surgery, cross-linking, and chronic postsurgical corneal edema).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Platelet-rich plasma eye drops shows to be a good option for the treatment of dormant corneal ulcers secondary to corneal surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672117747042","type":"journal-article","created":{"date-parts":[[2018,3,23]],"date-time":"2018-03-23T03:10:34Z","timestamp":1521774634000},"page":"515-520","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":30,"title":["Treatment with platelet-rich plasma of surgically related dormant corneal ulcers"],"prefix":"10.1177","volume":"28","author":[{"given":"Jorge L","family":"Alio","sequence":"first","affiliation":[{"name":"Research, Development and Innovation Department, VISSUM, Alicante, Spain"},{"name":"Faculty of Medicine, Miguel Hernandez University, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra E","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Cornea and Refractive Surgery, VISSUM, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"De Arriba","sequence":"additional","affiliation":[{"name":"Research, Development and Innovation Department, VISSUM, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Gisbert","sequence":"additional","affiliation":[{"name":"Department of Cornea and Refractive Surgery, VISSUM, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed 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