{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T04:38:48Z","timestamp":1794285528923,"version":"4.9.0"},"reference-count":9,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2018,6,11]],"date-time":"2018-06-11T00:00:00Z","timestamp":1528675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>Over-filtration is a well-known complication of trabeculectomy and related procedures, especially with adjunctive antimetabolites. Secondary hypotony can result in reduced visual acuity and compromise long-term surgical success. Persistent hypotony requires intervention and we describe an effective adaptation of placing conjunctival compression sutures directly over the scleral flap.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective consecutive case series of all patients who underwent conjunctival compression suturing from 2012 to 2014 at Manchester Royal Eye Hospital, UK. Under sub-tenon\u2019s anaesthesia, two 9\/0 nylon figure-of-eight transconjunctival sutures were placed horizontally across the bleb: the first over the anterior flap\/ostium and the second over the posterior flap edge to reduce flow through the trabeculectomy flap.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 10 patients underwent conjunctival compression suturing, and all patients had successful reversal of hypotony and symptom resolution within 1\u2009week with corresponding clinical improvement. Intraocular pressure control was maintained without topical pressure-lowering agents in seven patients (median\u2009=\u200910\u2009mmHg, range\u2009=\u20097\u201312\u2009mmHg) with a median follow-up of 35.9\u2009months (range\u2009=\u200911\u201361\u2009months). Two patients required topical therapy to maintain intraocular pressure\u2009\u2264\u200914\u2009mmHg and one patient\u2019s hypotony returned after 10\u2009months but remained untreated due to pre-existing poor vision. No patients required a return to theatre.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This series demonstrates that conjunctival compression sutures can successfully provide long-term control of trabeculectomy-bleb-related hypotony. This technique offers an effective alternative for glaucoma surgeons in addressing post-trabeculectomy hypotony.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672118777100","type":"journal-article","created":{"date-parts":[[2018,6,11]],"date-time":"2018-06-11T06:27:08Z","timestamp":1528698428000},"page":"731-734","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Conjunctival bleb compression sutures: An effective method of addressing hypotony after trabeculectomy or trabeculectomy-related procedures"],"prefix":"10.1177","volume":"28","author":[{"given":"Jonathan TS","family":"Yu","sequence":"first","affiliation":[{"name":"Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Mercieca","sequence":"additional","affiliation":[{"name":"Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leon","family":"Au","sequence":"additional","affiliation":[{"name":"Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,6,11]]},"reference":[{"key":"bibr1-1120672118777100","doi-asserted-by":"publisher","DOI":"10.1097\/00004397-200001000-00013"},{"key":"bibr2-1120672118777100","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.8.872"},{"key":"bibr3-1120672118777100","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-007-0694-2"},{"key":"bibr4-1120672118777100","doi-asserted-by":"publisher","DOI":"10.5301\/ejo.5000274"},{"key":"bibr5-1120672118777100","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2013-303357"},{"key":"bibr6-1120672118777100","first-page":"S444","volume":"37","author":"Palmberg P","year":"1996","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bibr7-1120672118777100","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0157320"},{"key":"bibr8-1120672118777100","doi-asserted-by":"publisher","DOI":"10.1097\/00061198-199912000-00008"},{"key":"bibr9-1120672118777100","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2012.12.004"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672118777100","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1120672118777100","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672118777100","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:43:55Z","timestamp":1777405435000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1120672118777100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,11]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1177\/1120672118777100"],"URL":"https:\/\/doi.org\/10.1177\/1120672118777100","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,11]]}}}