{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:31:54Z","timestamp":1777581114476,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,8,27]],"date-time":"2018-08-27T00:00:00Z","timestamp":1535328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the intraocular pressure\u2013lowering effect, the safety profile, and the success rate of the XEN45 Gel Stent (Allergan, Dublin, Ireland) in patients with pseudoexfoliative glaucoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective study conducted on patients with pseudoexfoliative glaucoma, with or without cataract, who underwent XEN45 implantation surgery with subconjunctival mitomycin-C and had a minimum postoperative follow-up period of 12\u2009months. The primary outcome measure was intraocular pressure reduction at 1\u2009year as compared to baseline. Complete success was defined as a postoperative intraocular pressure reduction of \u2a7e20% from preoperative baseline at 12\u2009months without any glaucoma medications. Qualified success was defined as a postoperative intraocular pressure reduction of \u2a7e20% at 12\u2009months with medications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of the 24 screened patients, 21 eyes of 20 patients met the inclusion\/exclusion criteria and were included in the study. A total of 13 (62%) eyes underwent XEN alone surgery and 8 (38%) eyes had combined XEN\u2009+\u2009cataract surgery. Mean intraocular pressure was significantly reduced from 21.1 (3.8)\u2009mmHg at baseline to 15.2 (3.9)\u2009mmHg at 1\u2009year, p\u2009&lt;\u20090.001. Mean antiglaucoma medications dropped from 2.95 (0.97) preoperatively to 1.23 (1.22) at month 12 (p\u2009&lt;\u20090.001). Of the 21 eyes included in the study, 18 (85.7%) were considered as success, 6 (28.6%) as complete success, and 12 (57.1%) as qualified success. Five eyes required needling revision. Complications included uveitis, choroidal detachment, hyphema, and cystoid macular edema in 2, 1, 1, and 1 eye, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>XEN45 Gel Stent implant significantly reduced the intraocular pressure and the number of antiglaucoma medications in patients with pseudoexfoliative glaucoma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672118795063","type":"journal-article","created":{"date-parts":[[2018,8,27]],"date-time":"2018-08-27T03:52:41Z","timestamp":1535341961000},"page":"309-314","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":37,"title":["One-year follow-up of the XEN\u00ae implant with mitomycin-C in pseudoexfoliative glaucoma patients"],"prefix":"10.1177","volume":"29","author":[{"given":"Ana","family":"Ib\u00e1\u00f1ez-Mu\u00f1oz","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, San Pedro Hospital, Logro\u00f1o, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00edctor Santiago","family":"Soto-Biforcos","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, San Pedro Hospital, Logro\u00f1o, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Chac\u00f3n-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, San Pedro Hospital, Logro\u00f1o, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar","family":"R\u00faa-Galisteo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, San Pedro Hospital, Logro\u00f1o, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Arrieta-Los 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