{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:32:41Z","timestamp":1777581161725,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,11,8]],"date-time":"2018-11-08T00:00:00Z","timestamp":1541635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2020,1]]},"abstract":"\n Purpose:<\/jats:title>\n To evaluate the role of multimodal imaging in the diagnosis and monitoring of patients with osteogenesis imperfecta complicated with choroidal neovascularization.<\/jats:p>\n <\/jats:sec>\n \n Case report:<\/jats:title>\n A 28-year-old man, diagnosed with osteogenesis imperfecta, was referred 2\u2009months after the appearance of central scotoma and metamorphopsia in the right eye. The patient underwent a complete ophthalmological evaluation including visual acuity examination as well as ophthalmoscopy, spectral-domain optical coherence tomography, optical coherence tomography angiography, fundus autofluorescence imaging, fluorescein angiography and microperimetry. Complete examination revealed macular lacquer crack with subretinal haemorrhage. A further investigation with spectral-domain optical coherence tomography and fluorescein angiography revealed the presence of choroidal neovascularization without clear activity associated to the lacquer crack. After a 1-month follow-up, both visual acuity and retinal sensitivity improved spontaneously.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Collagen deficiency of osteogenesis imperfecta leads to fragility of the Bruch\u2019s membrane; tension forces probably act at this level determining ruptures with bleeding and choroidal neovascularization formation. Multimodal imaging and functional evaluation are needed to assess retinal alterations in patients with osteogenesis imperfecta, whereas treatment of choroidal neovascularization should be reserved only for active lesion to prevent evolution and visual acuity decrement.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/1120672118811247","type":"journal-article","created":{"date-parts":[[2018,11,9]],"date-time":"2018-11-09T00:20:58Z","timestamp":1541722858000},"page":"NP21-NP24","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Multimodal imaging in a young male with osteogenesis imperfecta complicated with choroidal neovascularization"],"prefix":"10.1177","volume":"30","author":[{"given":"Riccardo Francesco","family":"Bellanca","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Campus Bio-Medico University, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Scarinci","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, IRCCS - Fondazione Bietti, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariacristina","family":"Parravano","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, IRCCS - Fondazione Bietti, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,11,8]]},"reference":[{"key":"bibr1-1120672118811247","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.16.2.101"},{"key":"bibr2-1120672118811247","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1982.01030040437014"},{"key":"bibr3-1120672118811247","doi-asserted-by":"publisher","DOI":"10.4103\/0301-4738.95882"},{"key":"bibr4-1120672118811247","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13242"},{"key":"bibr5-1120672118811247","doi-asserted-by":"publisher","DOI":"10.1364\/OE.20.004710"},{"key":"bibr6-1120672118811247","first-page":"191","volume":"104","author":"Kaiser-Kupfer MI","year":"1985","journal-title":"Trans Ophthalmol Soc U K"},{"key":"bibr7-1120672118811247","doi-asserted-by":"publisher","DOI":"10.1046\/j.1475-1313.2002.00062.x"},{"key":"bibr8-1120672118811247","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-006-9012-y"},{"key":"bibr9-1120672118811247","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(84)34116-1"},{"key":"bibr10-1120672118811247","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-199616030-00003"},{"key":"bibr11-1120672118811247","doi-asserted-by":"publisher","DOI":"10.3129\/i09-107"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672118811247","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1120672118811247","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672118811247","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:44:12Z","timestamp":1777405452000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1120672118811247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,8]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1177\/1120672118811247"],"URL":"https:\/\/doi.org\/10.1177\/1120672118811247","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,8]]}}}