{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:36:45Z","timestamp":1785458205714,"version":"3.56.0"},"reference-count":34,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T00:00:00Z","timestamp":1566432000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>To report the spectrum and frequency of conjunctiva tumours in an ocular oncology unit analysing the clinical profile of benign, precancerous and malignant conjunctival lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective case series of 462 consecutive patients diagnosed at the Ocular Oncology Unit of the University Hospital of Valladolid from 1992 to 2017.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among 462 consecutive patients, the tumour was classified as melanocytic in 252 (54.5%) and non-melanocytic in 210 (45.5). Two hundred forty-eight males (mean age 51.63 (SD\u2009=\u200923.20)) and 214 females (mean age 48.27 (SD\u2009=\u200921.77)) were included. Mean patient age at diagnosis was 50.07\u2009years (range = 1-92 years). The majority of tumours were benign (n\u2009=\u2009307 (66.5%)) followed by precancerous (n\u2009=\u2009103 (22.3%)) and finally by malignant ones (n\u2009=\u200952 (11.3%)). Benign lesions were predominantly found in younger individuals rather than premalignant (p\u2009&lt;\u20090.05) and malignant ones (p\u2009&lt;\u20090.05). Most of the melanocytic lesions were benign (88.5%), most epithelial ones were precancerous (61.4%) and most lymphoid lesions were malignant (56.3%). Tumours involving one or four quadrants of the ocular surface usually were benign, unlike tumours involving three quadrants that were malignant (16 (48.5%) p\u2009&lt;\u20090.05). The majority of benign lesions were detected on females (n\u2009=\u2009163 (53.1%)) by routine examination (n\u2009=\u2009178 (86.4%)). However, main complaint in malignant tumours was the growth of the lesion (n\u2009=\u200939 (76.5%)).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Most of the conjunctival tumours were melanocytic, mostly benign, closely followed by those of epithelial origin, with a predominance of precancerous lesions. Melanocytic, epithelial and lymphoid tumours accounted for over 90% of cases. A trend was identified with benign lesions being found in younger female patients on routine examination.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672119870736","type":"journal-article","created":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T07:28:44Z","timestamp":1566458924000},"page":"1403-1409","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Spectrum of conjunctival tumours in a Spanish series: A review of 462 cases"],"prefix":"10.1177","volume":"30","author":[{"given":"Luis","family":"Garc\u00eda Onrubia","sequence":"first","affiliation":[{"name":"Ocular Oncology Unit, Ophthalmology Department, Hospital Cl\u00ednico Universitario de Valladolid, Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela Estefan\u00eda","family":"Pacheco-Callirgos","sequence":"additional","affiliation":[{"name":"Ocular Oncology Unit, Ophthalmology Department, 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