{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:34:30Z","timestamp":1777581270189,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T00:00:00Z","timestamp":1567123200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>\n                      To evaluate the imaging characteristics of choroidal melanoma before and after proton beam radiotherapy via Optos\n                      <jats:sup>\u00ae<\/jats:sup>\n                      ultra-wide-field scanning laser ophthalmoscopy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective, descriptive study of choroidal melanoma patients treated with proton beam radiotherapy. All patients underwent full clinical evaluation, including best-corrected visual acuity, ultrasound examination and ultra-wide-field scanning laser ophthalmoscopy imaging in the pseudo-colour (red and green channel) as well as auto-fluorescence mode. Tumours were classified and evaluated according to their location, size, presence of subretinal fluid, drusen, orange pigment and reflectance intensity in ultra-wide-field scanning laser ophthalmoscopy. Tumour sonographic (basal diameter, height) and ultra-wide-field scanning laser ophthalmoscopy imaging dimensions (maximal diameter) were documented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 39 eyes (38 patients) were followed for 24\u2009months (range 6\u201348\u2009months). Mean best-corrected visual acuity dropped from 20\/40 to 20\/63 after proton beam radiotherapy. There was no change in the imaging tumour characteristics during follow-up. Subretinal fluid changes were better detected in the autofluorescence compared to pseudo-colour mode. Mean tumour diameter did not significantly change in the ultra-wide-field scanning laser ophthalmoscopy although it did so in the ultrasound. No patient showed local tumour recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      The ultra-wide-field scanning laser ophthalmoscopy imaging characteristics of choroidal melanoma in the Optos\n                      <jats:sup>\u00ae<\/jats:sup>\n                      system do not significantly change after proton beam radiotherapy after a mean follow-up of 2\u2009years.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672119873210","type":"journal-article","created":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T04:03:52Z","timestamp":1567137832000},"page":"1397-1402","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Ultra-wide-field imaging of choroidal melanoma before and after proton beam radiation therapy"],"prefix":"10.1177","volume":"30","author":[{"given":"Angeliki","family":"Psomiadi","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Medical University Innsbruck, Innsbruck, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gertrud","family":"Haas","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Medical University Innsbruck, Innsbruck, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Edlinger","sequence":"additional","affiliation":[{"name":"Department of Medical Statistics, Informatics, and Health Economics, Medical University Innsbruck, Innsbruck, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos E","family":"Bechrakis","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Blatsios","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Medical University Innsbruck, Innsbruck, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,8,30]]},"reference":[{"key":"bibr1-1120672119873210","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2015.10.005"},{"key":"bibr2-1120672119873210","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(80)35212-3"},{"key":"bibr3-1120672119873210","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(02)04200-1"},{"key":"bibr4-1120672119873210","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2012.249"},{"key":"bibr5-1120672119873210","first-page":"1667","volume":"5","author":"Seidensticker F","year":"2011","journal-title":"Clin 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