{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:35:14Z","timestamp":1777581314276,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2019,11,24]],"date-time":"2019-11-24T00:00:00Z","timestamp":1574553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To report the en-face choroidal vascularity index in healthy eyes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Thirty eyes of 30 healthy individuals were studied. Multiple high-density cross-sectional swept source optical coherence tomography scans were obtained to create a volume scan. The choroid was segmented for the whole volume scan and choroidal inner boundaries were flattened. Subsequently, multiple en-face scans separated by 25\u2009\u00b5m were obtained and binarized. Choroidal vascularity index was calculated at level of choriocapillaris, medium, and large choroidal vessels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean age of the study cohort was 35.6\u2009\u00b1\u20098.8\u2009years. The overall mean en-face choroidal vascularity index was 54.25\u2009\u00b1\u20090.55%. There was a statistically significant difference of choroidal vascularity index in choriocapillaris (53.16\u2009\u00b1\u20090.43%), medium choroidal vessel (51.38\u2009\u00b1\u20090.27%), and large choroidal vessel (55.69\u2009\u00b1\u20090.87%) (p\u2009&lt;\u20090.01). Choroidal vascularity index analysis in three subgroups based on subfoveal choroidal thickness (low: &lt;300\u2009\u00b5m, medium: 300\u2013400\u2009\u00b5m, high: &gt;400\u2009\u00b5m) showed a statistically significant difference (p\u2009=\u20090.001). Choroidal vascularity index showed a significant correlation with subfoveal choroidal thickness (r\u2009=\u20090.441; p\u2009=\u20090.015), whereas there was no significant correlation of age (p\u2009=\u20090.21), refraction (p\u2009=\u20090.20), and gender (p\u2009=\u20090.67) with en-face choroidal vascularity index.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>En-face choroidal vascularity index shows a significant variation at the level of choriocapillaris, medium choroidal vessel, and large choroidal vessel in normal eyes. Choroidal vascularity index reaches a nadir at the level of medium choroidal vessel and reaches the maximum value at large choroidal vessel near choroidoscleral interface. En-face choroidal vascularity index shows a significant physiological variation and appears to increase with increase in subfoveal choroidal thickness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672119883593","type":"journal-article","created":{"date-parts":[[2019,11,25]],"date-time":"2019-11-25T00:24:22Z","timestamp":1574641462000},"page":"218-225","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["En-face choroidal vascularity map of the macula in healthy eyes"],"prefix":"10.1177","volume":"31","author":[{"given":"Sumit Randhir","family":"Singh","sequence":"first","affiliation":[{"name":"Smt. Kanuri Santhamma Centre for Vitreo Retinal Diseases, L V Prasad Eye Institute, Hyderabad, India"},{"name":"Retina and Uveitis Department, L V Prasad Eye Institute, Visakhapatnam, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed Abdul","family":"Rasheed","sequence":"additional","affiliation":[{"name":"Smt. Kanuri Santhamma Centre for Vitreo Retinal Diseases, L V Prasad Eye Institute, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nishad","family":"Parveen","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering, Indian Institute of Technology Hyderabad, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhilash","family":"Goud","sequence":"additional","affiliation":[{"name":"Smt. Kanuri Santhamma Centre for Vitreo Retinal Diseases, L V Prasad Eye Institute, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samatha","family":"Ankireddy","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Missouri\u2013Kansas City, Kansas City, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niroj Kumar","family":"Sahoo","sequence":"additional","affiliation":[{"name":"Smt. Kanuri Santhamma Centre for Vitreo Retinal Diseases, L V Prasad Eye Institute, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiran Kumar","family":"Vupparaboina","sequence":"additional","affiliation":[{"name":"Srujana Innovation Center, L V Prasad Eye Institute, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soumya","family":"Jana","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering, Indian Institute of Technology Hyderabad, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jay","family":"Chhablani","sequence":"additional","affiliation":[{"name":"Smt. 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