{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:49:02Z","timestamp":1791402542863,"version":"4.3.3"},"reference-count":11,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T00:00:00Z","timestamp":1580774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100005242","name":"heed ophthalmic foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005242","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Optic disc pits frequently lead to visual deterioration due to macular retinoschisis or serous retinal detachment. Here, we report a case of optic disc pit\u2013associated macular retinoschisis due to intraretinal fluid accumulation that resolved with improvement in visual acuity after treatment with topical dorzolamide.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case description:<\/jats:title>\n                    <jats:p>A 56-year-old otherwise healthy female with no ocular history presented with 2\u2009weeks of slowly worsening blurry vision in her right eye. Visual acuity was 20\/30 in the right eye. Posterior segment examination revealed posterior vitreous detachment, an optic disc pit at 9 o\u2019clock, macular edema and foveoschisis with fluid extending from the optic nerve, and a normal peripheral retina. Optical coherence tomography imaging of the macula showed central subfield thickness of 526\u2009\u00b5m. The patient preferred no surgical intervention, so topical dorzolamide 2% three times daily was initiated. Over the next 2 years, the central subfield thickness steadily declined from 526 to 262\u2009\u00b5m, and her vision improved to 20\/20 with improvement in the macular retinoschisis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our report presents a case of resolution of optic disc pit\u2013associated macular retinoschisis due to intraretinal fluid accumulation with possible role for dorzolamide as a potential treatment option.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672120904664","type":"journal-article","created":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T01:43:51Z","timestamp":1580867031000},"page":"NP25-NP28","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Resolution of optic disc pit\u2013associated macular retinoschisis after topical carbonic anhydrase inhibitor treatment: Report of a case"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5435-8804","authenticated-orcid":false,"given":"Ahmad","family":"Al-Moujahed","sequence":"first","affiliation":[{"name":"Byers Eye Institute, Horngren Family Vitreoretinal Center, Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia F","family":"Callaway","sequence":"additional","affiliation":[{"name":"Byers Eye Institute, Horngren Family Vitreoretinal Center, Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8769-2369","authenticated-orcid":false,"given":"Daniel","family":"Vail","sequence":"additional","affiliation":[{"name":"Byers Eye Institute, Horngren Family Vitreoretinal Center, Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9586-3735","authenticated-orcid":false,"given":"Cassie A","family":"Ludwig","sequence":"additional","affiliation":[{"name":"Byers Eye Institute, Horngren Family Vitreoretinal Center, Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7033-7763","authenticated-orcid":false,"given":"Marco H","family":"Ji","sequence":"additional","affiliation":[{"name":"Byers Eye Institute, Horngren Family Vitreoretinal Center, Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2254-292X","authenticated-orcid":false,"given":"Darius M","family":"Moshfeghi","sequence":"additional","affiliation":[{"name":"Byers Eye Institute, Horngren Family Vitreoretinal Center, Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,2,4]]},"reference":[{"key":"bibr1-1120672120904664","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2014.06.001"},{"key":"bibr2-1120672120904664","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-011-1698-5"},{"key":"bibr3-1120672120904664","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1996.01100130159008"},{"key":"bibr4-1120672120904664","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-006-0267-9"},{"key":"bibr5-1120672120904664","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0503021102"},{"key":"bibr6-1120672120904664","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2009.398"},{"key":"bibr7-1120672120904664","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3182215ae9"},{"key":"bibr8-1120672120904664","doi-asserted-by":"publisher","DOI":"10.1080\/08820538.2016.1228404"},{"key":"bibr9-1120672120904664","first-page":"25","author":"Das 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