{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T22:28:43Z","timestamp":1783722523755,"version":"3.55.0"},"reference-count":9,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,2,16]],"date-time":"2020-02-16T00:00:00Z","timestamp":1581811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p>A number of systemic medications are known to cause macular toxicity, and bull\u2019s eye maculopathy is caused by some of them like hydroxychloroquine and clofazimine. A 55-year-old female, known case of vitiligo with history of undergoing methoxsalen\u2013ultraviolet A therapy, presented with painless defective vision in both eyes. Fundus examination and autofluorescence showed macular degeneration with bull\u2019s eye configuration. Optical coherence tomography showed perifoveal loss of photoreceptors and outer retinal thinning with foveal sparing appearing as \u2018flying saucer\u2019. Multifocal electroretinogram showed pan-macular suppression of waveforms. Patient was diagnosed as case of methoxsalen-induced advanced macular toxicity. This is the first reported case of methoxsalen-induced advanced bull\u2019s eye maculopathy.<\/jats:p>","DOI":"10.1177\/1120672120907317","type":"journal-article","created":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T01:55:31Z","timestamp":1581904531000},"page":"NP70-NP73","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Methoxsalen-induced advanced bull\u2019s eye maculopathy"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9410-4649","authenticated-orcid":false,"given":"Ratnesh","family":"Ranjan","sequence":"first","affiliation":[{"name":"Department of Vitreo-Retina Services, Aravind Eye Hospitals & Postgraduate Institute of Ophthalmology, Coimbatore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George J","family":"Manayath","sequence":"additional","affiliation":[{"name":"Department of Vitreo-Retina Services, Aravind Eye Hospitals & Postgraduate Institute of Ophthalmology, Coimbatore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9145-6964","authenticated-orcid":false,"given":"Romit","family":"Salian","sequence":"additional","affiliation":[{"name":"Department of Vitreo-Retina Services, Aravind Eye Hospitals & Postgraduate Institute of Ophthalmology, Coimbatore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkatapathy","family":"Narendran","sequence":"additional","affiliation":[{"name":"Department of Vitreo-Retina Services, Aravind Eye Hospitals & Postgraduate Institute of Ophthalmology, Coimbatore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,2,16]]},"reference":[{"key":"bibr1-1120672120907317","first-page":"147","volume":"35","author":"Bulat V","year":"2011","journal-title":"Coll Antropol"},{"key":"bibr2-1120672120907317","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)76619-X"},{"key":"bibr3-1120672120907317","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200767010-00006"},{"key":"bibr4-1120672120907317","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S14257"},{"key":"bibr5-1120672120907317","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.37719"},{"key":"bibr6-1120672120907317","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12696677"},{"key":"bibr7-1120672120907317","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.144143"},{"key":"bibr8-1120672120907317","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_413_17"},{"key":"bibr9-1120672120907317","doi-asserted-by":"publisher","DOI":"10.4103\/0976-500X.189685"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672120907317","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1120672120907317","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672120907317","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:45:23Z","timestamp":1777405523000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1120672120907317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,16]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1177\/1120672120907317"],"URL":"https:\/\/doi.org\/10.1177\/1120672120907317","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,16]]}}}