{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:36:43Z","timestamp":1777581403206,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T00:00:00Z","timestamp":1588032000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To report a rare case of intraocular schwannoma with extrascleral extension in a patient with juvenile idiopathic arthritis and to review the literature for this topic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Case report.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A 19-year-old male with a history of juvenile idiopathic arthritis was referred for diagnosis and management of an episcleral mass, initially thought to be focal nodular scleritis. The ocular surface of the right eye revealed an elevated amelanotic episcleral nodule inferonasally, with thin strands of overlying sclera, feeding episcleral vessels, and measuring 11\u2009mm\u2009\u00d7\u200911\u2009mm in diameter and 5\u2009mm in thickness. Ophthalmoscopic examination revealed a minimally pigmented ciliochoroidal tumor measuring 13\u2009mm in diameter and 11.4\u2009mm in total thickness and without associated subretinal fluid, orange pigment, or drusen. Ultrasound biomicroscopy and anterior-segment optical coherence tomography confirmed a solid mass with scleral disruption and extraocular extension. Shave biopsy revealed palisading spindle cells and interspersed eosinophilic fibrillary cytoplasmic processes, forming Verocay bodies. The specimen stained positive for S-100 and negative for Melan-A, consistent with benign schwannoma. Observation was recommended.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Intraocular schwannoma is a rare, benign uveal tumor that can demonstrate extrascleral extension, mimicking inflammatory and malignant neoplastic processes. Clinical diagnosis is challenging, and tissue biopsy is required for definite diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672120920211","type":"journal-article","created":{"date-parts":[[2020,4,29]],"date-time":"2020-04-29T02:19:37Z","timestamp":1588126777000},"page":"NP9-NP13","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Intraocular schwannoma with extrascleral extension"],"prefix":"10.1177","volume":"31","author":[{"given":"Sanika","family":"Udyaver","sequence":"first","affiliation":[{"name":"Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Anne S","family":"Lim","sequence":"additional","affiliation":[{"name":"Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatyana","family":"Milman","sequence":"additional","affiliation":[{"name":"Pathology Department, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arman","family":"Mashayekhi","sequence":"additional","affiliation":[{"name":"Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerry A","family":"Shields","sequence":"additional","affiliation":[{"name":"Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3288-3632","authenticated-orcid":false,"given":"Carol L","family":"Shields","sequence":"additional","affiliation":[{"name":"Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,4,28]]},"reference":[{"key":"bibr1-1120672120920211","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2012.04.003"},{"key":"bibr2-1120672120920211","doi-asserted-by":"publisher","DOI":"10.1007\/BF01853721"},{"key":"bibr3-1120672120920211","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2005.00517.x"},{"key":"bibr4-1120672120920211","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2005.12.004"},{"key":"bibr5-1120672120920211","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2013.11.017"},{"key":"bibr6-1120672120920211","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23329"},{"key":"bibr7-1120672120920211","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e31824d09a8"},{"key":"bibr8-1120672120920211","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000041"},{"key":"bibr9-1120672120920211","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(94)31249-8"},{"key":"bibr10-1120672120920211","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-016-1583-8"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672120920211","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1120672120920211","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672120920211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:45:33Z","timestamp":1777405533000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1120672120920211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,28]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1177\/1120672120920211"],"URL":"https:\/\/doi.org\/10.1177\/1120672120920211","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,28]]}}}