{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:39:31Z","timestamp":1777581571044,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T00:00:00Z","timestamp":1593734400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To study the type of bacteria and their antibiotic susceptibility pattern from corneal scrapings of patients with infectious keratitis presenting with concurrent nasolacrimal duct obstruction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective analysis was carried out of patients with microbial keratitis and co-existing nasolacrimal duct obstruction during a 5-year period (January 2012 to December 2016). Antibiotic susceptibility profile data was collected from the microbiology records.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The study included 56 (M:F\u2009=\u200933:23; OD:OS\u2009=\u200934:22) eyes. The mean age of patients was 60.2\u2009\u00b1\u200912.3\u2009years. Microscopic examination of corneal scrapings showed 52% of gram-positive ( n\u2009=\u200929\/55) and 2% of multiple (&gt;1; n\u2009=\u20091\/55) bacteria. Streptococcus pneumoniae (32%, n\u2009=\u200918\/56), coagulase-negative Staphylococcus (25%, n\u2009=\u200914\/56), and Staphylococcus aureus (11%, n\u2009=\u20096\/56) were the most common bacteria. Streptococcus pneumoniae was found to be susceptible to ciprofloxacin (72.2%), ofloxacin (94.4%), gatifloxacin (61.1%), and moxifloxacin (83.3%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Corneal infection associated with nasolacrimal duct obstruction is commonly caused by gram-positive-bacteria. Irrigation of nasolacrimal duct should be mandatory test in microbial keratitis. The gram-positive bacteria isolated showed maximum susceptibility to vancomycin and cefazolin. Early treatment by surgery and appropriate medical management is recommended for its control.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672120940574","type":"journal-article","created":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T04:33:56Z","timestamp":1593750836000},"page":"1720-1724","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Microbiological spectrum of microbial keratitis in patients presenting with nasolacrimal duct obstruction"],"prefix":"10.1177","volume":"31","author":[{"given":"Supriya","family":"Sharma","sequence":"first","affiliation":[{"name":"Cornea Service, LV Prasad Eye Institute, Bhubaneswar, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srikant K","family":"Sahu","sequence":"additional","affiliation":[{"name":"Cornea Service, LV Prasad Eye Institute, Bhubaneswar, Odisha, 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