{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:39:47Z","timestamp":1777581587705,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T00:00:00Z","timestamp":1594771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>To evaluate the safety and efficacy of new-generation hybrid contact lenses (HCL) among patients with irregular astigmatism.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      Medical records of 25 patients fit with new-generation HCL (Eyebrid\n                      <jats:sup>\u00ae<\/jats:sup>\n                      and AirFlex\n                      <jats:sup>\u00ae<\/jats:sup>\n                      ) were retrospectively reviewed. The data collected included etiology of irregular astigmatism, uncorrected visual acuity, manifest refraction, spectacle-corrected visual acuity (S-CDVA), steep \/ flat keratometric values, corneal astigmatism, records of rigid \/ soft CL fitted before HCL, all parameters of the trial lenses, and the final prescribed HCL parameters and HCL-CDVA.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The study included 34 eyes from 25 patients (nine females and 16 males) with an average age of 29 \u00b1 13 (ranging from 8\u201356) years. In total, 25 eyes with keratoconus, four with post - keratoplasty astigmatism, three with irregular astigmatism due to corneal trauma and two with residual astigmatism after radial keratotomy were fit with HCL. The mean S-CDVA (logMAR) improved significantly from 0.76 \u00b1 0.41 to 0.14 \u00b1 0.15 with HCL ( p &lt; 0.01). The most common indication for HCL was inability to fit with rigid gas permeable (RGP) lenses (22 eyes). The average number of lenses to successful fit was 1.4 (mode, 1; median, 1) and ideal fit was achieved with the first trial lens in 25 eyes (73%). Seven patients (nine eyes, 36%) discontinued lens use within the first 6\u2009months because of discomfort (six eyes, 24%), ocular allergy (two eyes, 8%) and tearing of contact lens (one eye, 4%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>New-generation HCL may be a suitable option for fitting challenging corneas with irregular astigmatism that cannot be rehabilitated efficiently with rigid lenses.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672120942757","type":"journal-article","created":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T02:29:45Z","timestamp":1594866585000},"page":"1802-1808","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Use of new-generation hybrid contact lenses for managing challenging corneas"],"prefix":"10.1177","volume":"31","author":[{"given":"Ibrahim Inan","family":"Harbiyeli","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Cukurova University, Adana, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elif","family":"Erdem","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Cukurova University, Adana, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Puren","family":"Isik","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Cukurova University, Adana, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meltem","family":"Yagmur","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Cukurova University, Adana, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reha","family":"Ersoz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Cukurova University, Adana, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,7,15]]},"reference":[{"issue":"1","key":"bibr1-1120672120942757","first-page":"35","volume":"2011","author":"Samra WA","journal-title":"Acta Ophthalmol"},{"key":"bibr2-1120672120942757","first-page":"747","volume":"82","author":"Irregular A.","year":"2007","journal-title":"Arch Soc Esp 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