{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T04:43:54Z","timestamp":1778561034707,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T00:00:00Z","timestamp":1595289600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>We report about a large retinal capillary hemangioma (RCH) with exudative retinal detachment and a macular fold, treated with Ruthenium-106 brachytherapy (Ru-106 BT) and scleral buckling surgery, followed by pars plana vitrectomy (PPV), for the removal of macular tractions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case description:<\/jats:title>\n                    <jats:p>A 17-year-old boy was referred to our Ocular Oncology Unit for a large RCH in the left eye. BCVA was hand motion. The RCH measured 4.9\u2009\u00d7\u20096.85\u2009mm in basal diameters and 4.0\u2009mm in thickness and was located in the mid-peripheral temporal retina. It was surrounded by extensive subretinal exudation, forming an exudative retinal detachment, with a retinal fold that extended from the lesion to the optic disc. We performed Ru-106 BT and at the moment of the plaque removal we placed a radial buckle with the aim to unbend the retinal fold. At 3-months follow-up the exudation decreased, we achieved the opening of the peripheral side of the retinal fold, but the macula was still detached. We decided to perform a lens sparing PPV, macular peeling and air tamponade, to remove the vitreoretinal tractions ab interno and to try to complete the opening of the macular fold. After 1-month BCVA was counting fingers, the retina appeared attached, also in the macular area, but the retinal fold remained partially close in the macular side. After 6\u2009months the tumor was inactivated, the macula remained attached, unfortunately, the macular fold remained partially close.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Ru-106 BT and scleral buckling concurrent approach can be an effective treatment modality in selected cases of large RCHs, followed by PPV to remove eventual vitreo-retinal tractions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672120944013","type":"journal-article","created":{"date-parts":[[2020,7,22]],"date-time":"2020-07-22T00:55:03Z","timestamp":1595379303000},"page":"NP75-NP80","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Combined brachytherapy and vitreoretinal surgery for a large retinal capillary hemangioma with exudative retinal detachment"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8835-9381","authenticated-orcid":false,"given":"Francesco","family":"Barca","sequence":"first","affiliation":[{"name":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7646-7422","authenticated-orcid":false,"given":"Giulio","family":"Vicini","sequence":"additional","affiliation":[{"name":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"},{"name":"Unit of Ocular Oncology, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Nicolosi","sequence":"additional","affiliation":[{"name":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"},{"name":"Unit of Ocular Oncology, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Pieretti","sequence":"additional","affiliation":[{"name":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"},{"name":"Unit of Ocular Oncology, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6902-2983","authenticated-orcid":false,"given":"Tomaso","family":"Caporossi","sequence":"additional","affiliation":[{"name":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanislao","family":"Rizzo","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli, Rome, Italy"},{"name":"Consiglio Nazionale della Ricerca, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrizio","family":"Giansanti","sequence":"additional","affiliation":[{"name":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"},{"name":"Department of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cinzia","family":"Mazzini","sequence":"additional","affiliation":[{"name":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"},{"name":"Unit of Ocular Oncology, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,7,21]]},"reference":[{"issue":"1","key":"bibr1-1120672120944013","first-page":"78","volume":"15","author":"Karimi S","year":"2020","journal-title":"J Ophthalmic Vis Res"},{"key":"bibr2-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(98)98017-4"},{"key":"bibr3-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(96)30696-9"},{"key":"bibr4-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e31817f2f00"},{"key":"bibr5-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.04.031"},{"key":"bibr6-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000707"},{"key":"bibr7-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000001240"},{"key":"bibr8-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000001562"},{"key":"bibr9-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1007\/s10633-016-9559-5"},{"key":"bibr10-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2014.08.009"},{"key":"bibr11-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(88)33080-0"},{"key":"bibr12-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/502143"},{"key":"bibr13-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1991.01080070078039"},{"key":"bibr14-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-17208-8_2"},{"key":"bibr15-1120672120944013","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e31826e86e0"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672120944013","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1120672120944013","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672120944013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:45:59Z","timestamp":1777405559000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1120672120944013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,21]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1177\/1120672120944013"],"URL":"https:\/\/doi.org\/10.1177\/1120672120944013","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,21]]}}}