{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T17:43:33Z","timestamp":1778867013900,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T00:00:00Z","timestamp":1596585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To assess long-term anatomic and functional outcomes of early lens-sparing vitrectomy (LSV) for stage 4A retinopathy of prematurity (ROP) in infants with aggressive-posterior ROP (AP-ROP) which progressed to retinal detachment despite laser treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Chart review of infants who underwent early 25-gage LSV for stage 4A ROP. Outcomes were anatomic success, mean visual acuity (VA), development of postoperative complications, and refractive changes. Follow-up examinations were performed at 1, 3, 6, 12, and then every 6\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Ten eyes of seven preterm infants who underwent LSV were included. Mean follow-up was 36\u2009\u00b1\u200913.4\u2009months and mean postmenstrual age (PMA) at last follow-up was 37\u2009\u00b1\u200913.7\u2009months. Mean gestational age (GA) and weight at birth was 26\u2009\u00b1\u20091.4\u2009weeks and 639\u2009\u00b1\u2009180\u2009g. Two eyes had vitreous hemorrhage 4 and 14\u2009days after surgery, respectively. At last follow-up anatomic success was 100%, mean VA was 20\/80 and eight eyes (80%) had high myopic refractive correction (mean spherical equivalent \u201311.25\u2009D).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Early LSV for stage 4A ROP with AP-ROP and progression to retinal detachment is efficacious in terms of anatomic and functional outcomes. Anatomic success is associated with visual improvement despite possible myopic refraction changes during follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672120946938","type":"journal-article","created":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T07:15:51Z","timestamp":1596611751000},"page":"2020-2026","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Lens-sparing vitrectomy for stage 4A retinopathy of prematurity in infants with aggressive-posterior ROP: Anatomic and functional results"],"prefix":"10.1177","volume":"31","author":[{"given":"Sara","family":"Macor","sequence":"first","affiliation":[{"name":"Department of Medicine \u2013 Ophthalmology, University of Udine, Udine, Italy"},{"name":"Department of Ophthalmology, Scientific Institute, IRCCS E. 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