{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:44:52Z","timestamp":1790671492517,"version":"4.1.0"},"reference-count":37,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T00:00:00Z","timestamp":1599609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To analyze the relationship between retinal nerve fiber layer thickness (RNFLT) and intraocular pressure (IOP) variation in glaucoma suspects (GS) and patients with primary open-angle glaucoma (POAG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Thirty-one GS and 34 POAG patients underwent ophthalmologic examination and 24-h IOP measurements. GS had IOPs ranging from 19 to 24\u2009mmHg and\/or suspicious appearance of the optic nerve. POAG patients had reproducible abnormal visual fields. We only included patients who presented with short-term IOP fluctuation &gt;6\u2009mm Hg (\u2206IOP). Only one eye per patient was included through a randomized process. Peripapillary RNFLT was assessed by spectral-domain optical coherence tomography. We correlated RNFLT with IOP parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Mean IOP was similar between GS and POAG groups (15.6\u2009\u00b1\u20093.47 vs 15.6\u2009\u00b1\u20092.83\u2009mmHg, p\u2009=\u20090.90) as was IOP peak at 6\u2009AM (21.7\u2009\u00b1\u20093.85 vs 21.3\u2009\u00b1\u20093.80\u2009mmHg, p\u2009=\u20090.68). Statistically significant negative correlations were found in POAG group between IOP at 6\u2009AM and RNFLT in global ( r\n                      <jats:sub>s<\/jats:sub>\n                      \u2009=\u2009\u22120.543; p\u2009&lt;\u20090.001), inferior ( r\n                      <jats:sub>s<\/jats:sub>\n                      \u2009=\u2009\u22120.540; p\u2009&lt;\u20090.001), superior ( r\n                      <jats:sub>s<\/jats:sub>\n                      \u2009=\u2009\u22120.405; p\u2009=\u20090.009), and nasal quadrants ( r\n                      <jats:sub>s<\/jats:sub>\n                      \u2009=\u2009\u22120.561; p\u2009&lt;\u20090.001). Negative correlations were also found between \u2206IOP and RNFLT in global ( r\n                      <jats:sub>s<\/jats:sub>\n                      \u2009=\u2009\u22120.591; p\u2009&lt;\u20090.001), and all other sectors ( p\u2009&lt;\u20090.05). In GS IOP at 6\u2009AM correlated only with inferior quadrant ( r\n                      <jats:sub>s<\/jats:sub>\n                      \u2009=\u2009\u22120.307; p\u2009=\u20090.047).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>IOP at 6\u2009AM and \u2206IOP had negative correlations with RNFLT quadrants in POAG. In GS this correlation occurred between IOP at 6\u2009AM and inferior quadrant. These findings may indicate potential risk factors for glaucoma progression.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672120957584","type":"journal-article","created":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T02:46:02Z","timestamp":1599705962000},"page":"2424-2431","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Correlation between retinal nerve fiber layer thickness and IOP variation in glaucoma suspects and patients with primary open-angle glaucoma"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1466-9963","authenticated-orcid":false,"given":"Sebasti\u00e3o","family":"Cronemberger","sequence":"first","affiliation":[{"name":"Visual Sciences Laboratory, Department of Ophthalmology and Otorhinolaryngology of the Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2771-3556","authenticated-orcid":false,"given":"Artur W","family":"Veloso","sequence":"additional","affiliation":[{"name":"Visual Sciences Laboratory, Department of Ophthalmology and Otorhinolaryngology of the Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil"},{"name":"Minas Gerais Research Foundation (FAPEMIG), Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christy","family":"Veiga","sequence":"additional","affiliation":[{"name":"Visual Sciences Laboratory, Department of Ophthalmology and Otorhinolaryngology of the Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"Scarpelli","sequence":"additional","affiliation":[{"name":"Visual Sciences Laboratory, Department of Ophthalmology and Otorhinolaryngology of the Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yara C","family":"Sasso","sequence":"additional","affiliation":[{"name":"Visual Sciences Laboratory, Department of Ophthalmology and Otorhinolaryngology of the Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8846-3610","authenticated-orcid":false,"given":"Rafael V","family":"Merola","sequence":"additional","affiliation":[{"name":"Visual Sciences Laboratory, Department of Ophthalmology and Otorhinolaryngology of the Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,9,9]]},"reference":[{"key":"bibr1-1120672120957584","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2007.07.005"},{"key":"bibr2-1120672120957584","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2016.07.006"},{"key":"bibr3-1120672120957584","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.01.017"},{"issue":"12","key":"bibr4-1120672120957584","first-page":"6457","volume":"57","author":"Cronemberger S","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bibr5-1120672120957584","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2014-305156"},{"key":"bibr6-1120672120957584","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-27492010000400009"},{"key":"bibr7-1120672120957584","volume-title":"Intraocular pressure, daily curve of intraocular pressure, sclera rigidity and tonographic coefficients (means, of normality in different age-groups)","author":"Calixto NC","year":"1967"},{"key":"bibr8-1120672120957584","first-page":"151","volume-title":"Automated static perimetry","author":"Anderson DR","year":"1999","edition":"2"},{"key":"bibr9-1120672120957584","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.82.8.971"},{"issue":"8","key":"bibr10-1120672120957584","first-page":"1186","volume":"26","author":"Ray WA","year":"1985","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bibr11-1120672120957584","unstructured":"Cioffi GA, Durcan FJ, Girkin CA. 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