{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:10:24Z","timestamp":1790835024040,"version":"4.1.0"},"reference-count":25,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T00:00:00Z","timestamp":1604275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To report the wide-field choroidal vessel analysis in central serous chrorioretinopathy (CSCR) and their fellow eyes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Wide-field optical coherence tomography (WF-OCT) images (55\u00b0) were obtained using Spectralis HRA + OCT (Heidelberg Engineering, Germany) in extremes of gazes in all quadrants and manual montages were created to obtain wide field images up to equator. Choroidal thickness (CT), large choroidal vessel layer thickness (LCVT), and choroidal vascularity index (CVI) were calculated in macular segment (twice the disc to fovea distance) and all four quadrants. Regression analysis was performed to identify the factors influencing CVI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Thirty-one patients of CSCR including 39 eyes of CSCR (32 chronic, 7 acute) and 23 fellow eyes were analyzed. CT and LCVT were significantly higher in submacular choroid than all extramacular segments in both CSCR and fellow eyes (all p values &lt;0.01). CVI varied significantly in different segments in horizontal ( p\u2009&lt;\u20090.01 in both) and vertical meridian ( p\u2009&lt;\u20090.01 and p\u2009=\u20090.01 respectively) in CSCR and fellow eyes. Both CSCR and fellow eyes had highest CVI in nasal segment with minimum CVI in macular segment. Age ( p\u2009=\u20090.85), gender ( p\u2009=\u20090.39), chronicity of the disease (acute vs chronic, p\u2009=\u20090.57), axial length ( p\u2009=\u20090.67), SBP ( p\u2009=\u20090.81), and DBP ( p\u2009=\u20090.94) were not significantly correlated to CVI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>CVI shows significant regional variation with macular segment showing the lowest CVI whereas nasal segments have highest CVI in both CSCR and their fellow eyes. On the contrary, submacular segment has highest CT and LCVT with taper towards periphery in both CSCR and fellow eyes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672120963456","type":"journal-article","created":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T06:05:48Z","timestamp":1604297148000},"page":"2520-2527","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Wide-field choroidal vascular analysis in central serous chorioretinopathy"],"prefix":"10.1177","volume":"31","author":[{"given":"Sumit Randhir","family":"Singh","sequence":"first","affiliation":[{"name":"Smt. Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L V Prasad Eye Institute, Hyderabad, Telangana, India"},{"name":"Retina and Uveitis Department, GMR Varalakshmi Campus, L V Prasad Eye Institute, Hanumanthawaka Junction, Visakhapatnam, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3400-1987","authenticated-orcid":false,"given":"Alessandro","family":"Invernizzi","sequence":"additional","affiliation":[{"name":"Eye Clinic, Department of Biomedical and Clinical Science \u201cLuigi Sacco\u201d, University of Milan, Milano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Abdul","family":"Rasheed","sequence":"additional","affiliation":[{"name":"Smt. Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L V Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3812-9219","authenticated-orcid":false,"given":"Carlo","family":"Cagini","sequence":"additional","affiliation":[{"name":"Department of Biochemical and Surgical Sciences, Section of Ophthalmology, University of Perugia, Perugia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhilash","family":"Goud","sequence":"additional","affiliation":[{"name":"Smt. Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L V Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramkailash","family":"Gujar","sequence":"additional","affiliation":[{"name":"Department of Biochemical and Surgical Sciences, Section of Ophthalmology, University of Perugia, Perugia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiran Kumar","family":"Vupparaboina","sequence":"additional","affiliation":[{"name":"Smt. 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Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L V Prasad Eye Institute, Hyderabad, Telangana, India"},{"name":"UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,11,2]]},"reference":[{"key":"bibr1-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1126\/science.1957169"},{"key":"bibr2-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-16670"},{"key":"bibr3-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.6.001534"},{"key":"bibr4-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2018.06.016"},{"key":"bibr5-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.12.035"},{"key":"bibr6-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2016.01.045"},{"key":"bibr7-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.08-2869"},{"key":"bibr8-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.8.000016"},{"key":"bibr9-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2012.07.051"},{"key":"bibr10-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2015.05.003"},{"key":"bibr11-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2016.03.040"},{"key":"bibr12-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2014.04.021"},{"key":"bibr13-1120672120963456","doi-asserted-by":"publisher","DOI":"10.4103\/jovr.jovr_152_17"},{"key":"bibr14-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-014-0034-6"},{"key":"bibr15-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0146344"},{"key":"bibr16-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1038\/srep21090"},{"key":"bibr17-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000001040"},{"key":"bibr18-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-35640-9"},{"key":"bibr19-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2018.11.002"},{"key":"bibr20-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.01.066"},{"key":"bibr21-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1016\/j.compmedimag.2015.09.008"},{"key":"bibr22-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13442"},{"key":"bibr23-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-39653-w"},{"key":"bibr24-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2009.12.002"},{"key":"bibr25-1120672120963456","doi-asserted-by":"publisher","DOI":"10.1016\/j.oret.2017.05.013"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672120963456","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1120672120963456","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672120963456","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:43:33Z","timestamp":1777405413000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1120672120963456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,2]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1177\/1120672120963456"],"URL":"https:\/\/doi.org\/10.1177\/1120672120963456","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,2]]}}}