{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:07:52Z","timestamp":1791317272999,"version":"4.3.1"},"reference-count":32,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2020,11,29]],"date-time":"2020-11-29T00:00:00Z","timestamp":1606608000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To investigate the effects of topical nepafenac on choroidal thickness (CT) following uneventful phacoemulsification surgery (UPS) using enhanced depth imaging optical coherence tomography (EDI-OCT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This prospective study included 45 randomly selected eyes (23 eyes of 23 patients used nepafenac (nepafenac group) and 22 eyes of 22 control patients did not use nepafenac (nepafenac-free group)) undergoing small-incision UPS. All participants underwent full ophthalmologic examination. CT measurements were performed at subfoveal, 1.0\u2009mm temporal, and 1.0\u2009mm nasal using the EDI-OCT preoperatively, 1\u2009day,\u20091 week, and 1\u2009month postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean subfoveal, nasal, and temporal CT in the nepafenac-free group had changed from 268.95\u2009\u00b1\u200963.59\u2009\u03bcm to 283.36\u2009\u00b1\u200965.63\u2009\u03bcm, 237.22\u2009\u00b1\u200964.09\u2009\u03bcm to 253.09\u2009\u00b1\u200967.27\u2009\u03bcm, and 235.95\u2009\u00b1\u200975.22\u2009\u03bcm to 259.09\u2009\u00b1\u200963.66\u2009\u03bcm preoperatively to 1\u2009month postoperatively, respectively ( p\u2009&lt;\u20090.001, p\u2009&lt;\u20090.001, p\u2009&lt;\u20090.001, respectively). The mean subfoveal, nasal, and temporal CT in the nepafenac group had changed from 259.65\u2009\u00b1\u200955.99\u2009\u03bcm to 276.65\u2009\u00b1\u200959.21\u2009\u03bcm, 236.34\u2009\u00b1\u200955.40\u2009\u03bcm to 251.00\u2009\u00b1\u200962.39\u2009\u03bcm, and 247.56\u2009\u00b1\u200950.88\u2009\u03bcm to 261.13\u2009\u00b1\u200953.73\u2009\u03bcm preoperatively to 1\u2009month postoperatively, respectively ( p\u2009&lt;\u20090.001, p\u2009&lt;\u20090.001, p\u2009&lt;\u20090.001, respectively). The postoperative CT continued to increase significantly during the follow-up period in two groups. However, compared to the change from baseline to month 1, there was not a statistically significant difference between the groups at subfoveal, nasal, and temporal CT ( p: 0.633, p: 0.865, and p: 0.328, respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>UPS may cause a significant increase in CT. Although increasing in the CT was lower in the nepafenac group than the nepafenac-free group, there was not a statistically significant difference between the groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672120976041","type":"journal-article","created":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T02:01:12Z","timestamp":1606701672000},"page":"2319-2328","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["How does nepafenac affect the choroidal thickness after uneventful cataract surgery?"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7968-4876","authenticated-orcid":false,"given":"Selim","family":"Cevher","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Department of Ophthalmology, Hitit University, \u00c7orum, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4653-4767","authenticated-orcid":false,"given":"G\u00fcl\u00e7in","family":"Aydo\u011fdu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Biostatistics, Hitit University, \u00c7orum, 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