{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:29:07Z","timestamp":1777580947951,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T00:00:00Z","timestamp":1607472000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To compare the outcomes of femtosecond laser assisted in situ keratomileusis (FS-LASIK) with transepithelial photorefractive keratectomy (T-PRK) for the correction of high-grade astigmatism.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Medical records of patients with astigmatism of 2\u2009diopters (D) or higher, who were treated with FS-LASIK or T-PRK in 2013 through 2014 at a private practice laser clinic, were retrospectively analyzed. Efficacy, safety, predictability and vector analysis of astigmatism correction were compared between the treatment groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The study included 93 eyes treated with FS-LASIK and 186 eyes treated with T-PRK. No significant differences in postoperative spherical equivalent (\u22120.10\u2009\u00b1\u20090.7\u2009D and \u22120.11\u2009\u00b1\u20090.7\u2009D, respectively, p\u2009=\u20090.958) and postoperative refractive astigmatism (0.79\u2009\u00b1\u20090.54\u2009D and 0.82\u2009\u00b1\u20090.63\u2009D, respectively, p\u2009=\u20090.685) were demonstrated. A significant advantage of FS-LASIK over T-PRK was seen for the efficacy (1.00\u2009\u00b1\u20090.18 and 0.86\u2009\u00b1\u20090.22, respectively, p\u2009&lt;\u20090.001) and safety (1.03\u2009\u00b1\u20090.17 and 0.89\u2009\u00b1\u20090.21, respectively, p\u2009&lt;\u20090.001) indices. Results remain statistically significant in a multivariate analysis model. Vector analysis for the astigmatism correction showed no significant difference between the surgery methods in the surgically induced astigmatism, difference vector, correction index and index of success.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Both procedures demonstrated desirable post-operative SE outcomes for high-grade astigmatism correction. However, FS-LASIK achieved better results than T-PRK in the efficacy and safety parameters.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672120978885","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T13:41:01Z","timestamp":1607607661000},"page":"2923-2931","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Refractive outcomes of high-magnitude astigmatism correction using femtosecond LASIK versus transepithelial PRK"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8417-4440","authenticated-orcid":false,"given":"Olga","family":"Reitblat","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel"},{"name":"Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 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