{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:29:09Z","timestamp":1777580949383,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T00:00:00Z","timestamp":1615248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To assess the tear film thickness in healthy individuals by using a dual-Scheimpflug camera and topical 0.1% fluorescein.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A prospective study on healthy individuals who underwent a bilateral tomography examination using the GALILEI dual-Scheimpflug with assessments of the thinnest and central corneal thickness (TCT and CCT, respectively), at baseline and 1\u2009min after applying 2 and 4\u2009\u00b5l of 0.1% fluorescein (30\u2009min apart) under topical anesthesia with Oxybuprocaine 0.4%. Inclusion criteria were lack of dry eye disease symptoms and exclusion criteria were contact lens usage, eye drops usage, previous refractive surgery or any ocular surgery. All individuals scored zero on the ocular surface disease index (OSDI) questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 62 eyes of 31 participants were included in this study. The mean age was 35.3\u2009\u00b1\u200910.88 (range 18\u201362). The mean TCT in was 549.16\u2009\u00b5m in the right eye (RE) and 547.84\u2009\u00b5m in the left eye (LE). After instillation of 2\u2009\u00b5l of 0.1% fluorescein mean TCT increase by 27.84\u2009\u00b5m in the RE and by 26.35\u2009\u00b5m in the LE. CCT change was 27.58\u2009\u00b5m increase in RE and 27.23\u2009\u00b5m increase in LE. After instillation of 4\u2009\u00b5l of 0.1% fluorescein the mean increase in TCT and CCT were 30.09 and 30.26\u2009\u00b5m for OD and 28.33 and 30.15\u2009\u00b5m for OS respectively. Comparison between the post instillation of 2 and 4\u2009\u00b5l measurements showed no significant differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Combining a dual-Scheimpflug camera and 0.1% fluorescein may serve as a method to assess the pre-corneal tear film.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721211000274","type":"journal-article","created":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T00:21:01Z","timestamp":1615335661000},"page":"160-164","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Applying a dual-Scheimpflug camera to measure tear film thickness"],"prefix":"10.1177","volume":"32","author":[{"given":"Shay","family":"Keren","sequence":"first","affiliation":[{"name":"Ophthalmology Department, Tel-Aviv Medical Center, Affiliated to the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel"},{"name":"Oxford Eye Hospital, John Radcliffe Hospital, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4661-0993","authenticated-orcid":false,"given":"Michael","family":"Mimouni","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Rambam Health Care Campus and the Bruce and Ruth Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewan","family":"McCallum","sequence":"additional","affiliation":[{"name":"Oxford Eye Hospital, John Radcliffe Hospital, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9206-8373","authenticated-orcid":false,"given":"Gilad","family":"Rabina","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Tel-Aviv Medical Center, Affiliated to the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliya","family":"Levinger","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Tel-Aviv Medical Center, Affiliated to the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,3,9]]},"reference":[{"key":"bibr1-11206721211000274","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-0124(12)70081-2"},{"key":"bibr2-11206721211000274","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000358"},{"key":"bibr3-11206721211000274","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199811000-00002"},{"key":"bibr4-11206721211000274","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-11920"},{"key":"bibr5-11206721211000274","first-page":"756","volume":"17","author":"Azartash K","year":"2011","journal-title":"Mol 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