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OCT angiography (OCTA) did not show the presence of vascular tissue, thus the hyperreflective material was ascribed to primary gliotic tissue. This case highlights the ability for M\u00fcller cells placed near macular holes to migrate up to the RPE and to produce gliotic tissue.<\/jats:p>","DOI":"10.1177\/11206721211029501","type":"journal-article","created":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T02:01:31Z","timestamp":1625018491000},"page":"NP47-NP49","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Gliotic tissue simulating a macular neovascularization in full-thickness macular hole"],"prefix":"10.1177","volume":"32","author":[{"given":"Chiara","family":"Vigano\u2019","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Borrelli","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2891-2012","authenticated-orcid":false,"given":"Riccardo","family":"Sacconi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7541-584X","authenticated-orcid":false,"given":"Maria","family":"Brambati","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3238-9682","authenticated-orcid":false,"given":"Francesco","family":"Bandello","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3292-9581","authenticated-orcid":false,"given":"Giuseppe","family":"Querques","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,6,29]]},"reference":[{"key":"bibr1-11206721211029501","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2002.800605.x"},{"key":"bibr2-11206721211029501","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.17-21756"},{"key":"bibr3-11206721211029501","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-020-01477-3"},{"key":"bibr4-11206721211029501","doi-asserted-by":"publisher","DOI":"10.3129\/can j ophthalmol.06-107"},{"key":"bibr5-11206721211029501","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-6-396"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721211029501","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/11206721211029501","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/11206721211029501","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:44:42Z","timestamp":1777405482000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/11206721211029501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,29]]},"references-count":5,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1177\/11206721211029501"],"URL":"https:\/\/doi.org\/10.1177\/11206721211029501","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,29]]}}}