{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T21:31:24Z","timestamp":1791322284604,"version":"4.3.1"},"reference-count":11,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T00:00:00Z","timestamp":1625616000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To describe optical coherence tomography angiography (OCTA) findings in the retina and choroid of patients with neurofibromatosis type 1 (NF1).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We describe a series of four patients diagnosed with NF1 and choroidal nodules who underwent a comprehensive ophthalmic evaluation including a retinal multimodal imaging study based on retinography, near-infrared reflectance imaging (NIR), enhanced depth imaging (EDI) optical coherence tomography (OCT) and OCTA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Patients were three women and one man aged 36\u201347 years. In all patients, the choroidal nodules were not visible in retinographies but easily detectable with NIR, appearing as multiple bright patches. On OCTA, we observed reduced vessel density in the choriocapillaris in zones where choroidal nodules appeared in OCT images. In one patient, a corkscrew vessel was visible in the superficial capillary plexus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Choriocapillaris vessel density was reduced in zones where choroidal nodules occur in NF1 patients. Further work is needed to clarify the clinical relevance of this finding.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721211030781","type":"journal-article","created":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T07:41:15Z","timestamp":1625643675000},"page":"NP91-NP94","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Optical coherence tomography angiography of choroidal nodules in neurofibromatosis type-1: A case series"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7748-0506","authenticated-orcid":false,"given":"Francisco Javier","family":"Moreno-Morillo","sequence":"first","affiliation":[{"name":"Ophthalmology Department and Health Research Institute (IdISSC), Hospital Clinico San Carlos, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8745-3464","authenticated-orcid":false,"given":"Jos\u00e9 Ignacio","family":"Fern\u00e1ndez-Vigo","sequence":"additional","affiliation":[{"name":"Ophthalmology Department and Health Research Institute (IdISSC), Hospital Clinico San Carlos, Madrid, Spain"},{"name":"Centro Internacional de Oftalmolog\u00eda Avanzada, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2178-6164","authenticated-orcid":false,"given":"B\u00e1rbara","family":"Burgos-Blasco","sequence":"additional","affiliation":[{"name":"Ophthalmology Department and Health Research Institute (IdISSC), Hospital Clinico San Carlos, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Llorente-La Orden","sequence":"additional","affiliation":[{"name":"Ophthalmology Department and Health Research Institute (IdISSC), Hospital 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