{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:34:43Z","timestamp":1777581283983,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T00:00:00Z","timestamp":1626134400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100007819","name":"Allergan","doi-asserted-by":"publisher","award":["PG-2020-10989"],"award-info":[{"award-number":["PG-2020-10989"]}],"id":[{"id":"10.13039\/100007819","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The aim of this study was to describe functional and anatomical changes (best-corrected visual acuity [BCVA], central macular thickness [CMT], and central macular volume [CMV]) in patients with macular edema (ME) secondary to retinal vein occlusion (RVO) treated with intravitreal dexamethasone implant (IDI) and identify its clinical predictors in a real-world setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Data from 111 patients who underwent IDI to treat RVO-associated ME were retrospectively reviewed. Demographic, preoperative, and postoperative variables were assessed using a logistic regression analysis to determine predictors of visual and anatomical improvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Mean BCVA, CMT, and CMV improved from baseline after IDI ( p\u2009&lt;\u20090.001). The strongest predictors of different treatment outcomes were: a baseline BCVA \u2a7d60 ETDRS letters (OR\u2009=\u200950.600; p\u2009&lt;\u20090.001) and first IDI injection (OR\u2009=\u20092.988; p\u2009&lt;\u20090.001) for BCVA gain \u2a7e15 Early Treatment Diabetic Retinopathy Study (ETDRS) letters; a baseline BCVA \u2a7d60 ETDRS letters (OR\u2009=\u20097.893; p\u2009=\u20090.002) and non-chronic ME (OR\u2009=\u20093.875; p\u2009=\u20090.019) for BCVA \u2a7e80 ETDRS letters achievement; a baseline CMT \u2a7e400\u2009\u00b5m (OR\u2009=\u200949.083; p\u2009 &lt;\u20090.001) and a baseline CMV \u2a7e12\u2009mm\n                      <jats:sup>3<\/jats:sup>\n                      (OR\u2009=\u20094.235; p\u2009&lt;\u20090.001) for CMT reduction \u2a7e50%; and a baseline CMT \u2a7e400\u2009\u00b5m (OR\u2009=\u200911.471; p\u2009 &lt;\u20090.001) and a baseline CMV \u2a7e12\u2009mm\n                      <jats:sup>3<\/jats:sup>\n                      (OR\u2009=\u200910.284; p\u2009&lt;\u20090.001) for CMV reduction \u2a7e15%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study confirmed the effectiveness of IDI to treat ME secondary to RVO and identified new predictive factors for two visual (\u2a7e15 ETDRS letters gain and BCVA \u2a7e80 ETDRS letters) and two anatomical outcomes (&gt;50% CMT and &gt;15% CMV reduction).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721211032520","type":"journal-article","created":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T07:12:18Z","timestamp":1626160338000},"page":"1671-1679","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Short-term effectiveness prognostic factors after dexamethasone intravitreal implant in macular edema due to retinal vein occlusion"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5255-8426","authenticated-orcid":false,"given":"Gonzaga","family":"Garay-Aramburu","sequence":"first","affiliation":[{"name":"Ophthalmology Department, Basurto University Hospital, Bilbao, Spain"},{"name":"Universidad del Pais Vasco-Euskal Herriko Unibertsitatea, Vitoria-Gasteiz, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1ngela","family":"G\u00f3mez-Moreno","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Araba University Hospital, Vitoria-Gasteiz, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aritz","family":"Urcola","sequence":"additional","affiliation":[{"name":"Universidad del Pais Vasco-Euskal Herriko Unibertsitatea, Vitoria-Gasteiz, Spain"},{"name":"Ophthalmology Department, Araba University Hospital, Vitoria-Gasteiz, 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