{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T11:57:29Z","timestamp":1785326249119,"version":"3.55.0"},"reference-count":37,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,8,12]],"date-time":"2021-08-12T00:00:00Z","timestamp":1628726400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To compare choroidal thickness (CT) and ocular pulse amplitude (OPA) in childhood obesity with insulin resistance (IR) and without IR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Seventy-three childhood obesity and 62 healthy children, who were both age-matched and gender-matched, comprised the study population in this prospective study. Obesity was determined as having a body mass index (BMI) \u2013 standard deviation (SD) score that was\u2009&gt;\u20092\u2009SD. Intraocular pressure (IOP) and OPA were measured using a dynamic contour tonometer. The CT measurements were performed using enhanced depth imaging optical coherence tomography at three locations, comprising at the fovea, at a position 500\u2009\u00b5m nasal, and also at a position 500\u2009\u00b5m temporal to the fovea.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Mean BMI value was 28.72\u2009\u00b1\u20094.85 in the patients with childhood obesity and 21.47\u2009\u00b1\u20091.14 in the control group. The mean IOP and OPA values were determined 15.90\u2009\u00b1\u20092.30 and 14.10\u2009\u00b1\u20092.16\u2009mm Hg, 1.50\u2009\u00b1\u20090.28 and 1.74\u2009\u00b1\u20090.32\u2009mm Hg in the patients with childhood obesity and the control group, respectively ( p\u2009&lt;\u20090.001, p\u2009&lt;\u20090.001). The mean subfoveal CT value was 350.50\u2009\u00b1\u200981.51\u2009\u03bcm in the eyes with childhood obesity and 390.02\u2009\u00b1\u200971.50\u2009\u03bcm in those of the control group ( p\u2009=\u20090.003). When the patient groups with and without IR were compared, no significant difference was found between CT, OPA and IOP values ( p\u2009&gt;\u20090.005).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Our results showed that both OPA and CT values were significantly decreased in childhood obesity patients. We suggest further studies to verify longitudinal changes in OPA and CT, as also the evaluation of these parameters in other populations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721211039337","type":"journal-article","created":{"date-parts":[[2021,8,12]],"date-time":"2021-08-12T05:54:01Z","timestamp":1628747641000},"page":"2018-2025","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Changes in ocular pulse amplitude and choroidal thickness in childhood obesity patients with and without insulin resistance"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5708-9283","authenticated-orcid":false,"given":"G\u00f6zde Aksoy","family":"Aydemir","sequence":"first","affiliation":[{"name":"Ophthalmology Department, Ad\u0131yaman University Education and Research Hospital, Ad\u0131yaman, 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