{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T08:00:27Z","timestamp":1790496027327,"version":"4.1.0"},"reference-count":39,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T00:00:00Z","timestamp":1632700800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>Cataract and glaucoma are among the leading causes of blindness worldwide in older people, and they are often concomitant. To assess topical intraocular (IOP)-lowering agents delivery changes after cataract extraction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods:<\/jats:title>\n                    <jats:p>Longitudinal matched exposed\u2013unexposed study from the French national healthcare database from January 1, 2005 to January 1, 2017. We compared individuals using topical IOP-lowering agents who underwent bilateral cataract extraction with individuals matched on IOP-lowering agents load, age, and sex who did not undergo cataract extraction. IOP-lowering agents number of drops was assessed 12 months before the first cataract extraction and compared with number of drops 12 months after the second cataract extraction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>About 1194 individuals treated with IOP-lowering agents were included, 597 exposed to bilateral cataract extraction and 597 unexposed to any surgery (total mean age 74.8 \u00b1 8.3 years; 69.0% women). Mean IOP-lowering agents delivery at baseline was 1.4 daily drops in both groups. The mean number of drops decreased greater in the exposed than unexposed group (\u221225.5% vs \u22123.5%; p &lt; 0.0001). Overall, 159 (26.6%) and 48 (8.0%) individuals in the exposed and unexposed groups interrupted medication ( p &lt; 0.0001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>A decrease of around one quarter of IOP-lowering agents delivery was observed after cataract extraction in the present real-life study with a longstanding interruption observed in one quarter of patients. Phacoemulsification as a standalone procedure reduces IOP-lowering agents delivery in ocular hypertension and glaucoma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721211044328","type":"journal-article","created":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T11:13:26Z","timestamp":1632741206000},"page":"2201-2210","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Cataract extraction and intraocular pressure-lowering agents delivery: A nationwide French study between 2005 and 2017"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0501-1932","authenticated-orcid":false,"given":"Chlo\u00e9","family":"Chamard","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Gui de Chauliac Hospital, Montpellier, France"},{"name":"Universit\u00e9 Montpellier, Inserm, Neuropsychiatry: Epidemiological and Clinical Research, PSNREC, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e9na","family":"Huguet","sequence":"additional","affiliation":[{"name":"Department of Clinical Investigation, CHU Montpellier, University of Montpellier, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain M","family":"Bron","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital, Dijon, France"},{"name":"Centre des Sciences du Go\u00fbt et de l'Alimentation, AgroSup Dijon, CNRS, INRAE, Universit\u00e9 Bourgogne Franche-Comt\u00e9, Dijon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Creuzot-Garcher","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital, Dijon, France"},{"name":"Centre des Sciences du Go\u00fbt et de l'Alimentation, AgroSup Dijon, CNRS, INRAE, Universit\u00e9 Bourgogne Franche-Comt\u00e9, Dijon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Nogue","sequence":"additional","affiliation":[{"name":"Department of Clinical Investigation, CHU Montpellier, University of Montpellier, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Villain","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Gui de Chauliac Hospital, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Nagot","sequence":"additional","affiliation":[{"name":"Department of Clinical Investigation, CHU Montpellier, University of Montpellier, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Carri\u00e8re","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Montpellier, Inserm, Neuropsychiatry: Epidemiological and Clinical Research, PSNREC, Montpellier, 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