{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T03:25:34Z","timestamp":1779247534341,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T00:00:00Z","timestamp":1633910400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To describe a new technique for sutureless and glue-free amniotic membrane transplantation (AMT) and to investigate its effectiveness to treat corneal persistent epithelial defects (PEDs), compared to bandage contact lens (BCL) application alone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed AMT with \u201ccontact lens sandwich technique\u201d (CLS-AMT) in 8 consecutive patients with central\/para-central (up to 4.00 mm from the geometrical centre) PED\/ulceration and we retrospectively compared the results with 11 BCL procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The procedures were performed successfully with no complications. CLS-AMT showed significantly shorter healing time than BCL (24.0\u2009\u2009\u00b1\u2009\u200919.1 vs 42.9\u2009\u2009\u00b1\u2009\u200914.6 days; P\u2009&lt;\u20090.05, Mann-Whitney test). Recurrence rates were 12% and 27% for CLS-AMT and BCL, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CLS-AMT technique, based on the suction effect due to the superposition of a bandage contact lens on the AM-ring complex, represents a quick, low cost, easy to perform and nearly non-invasive AMT technique. This approach is able to provide adequate fixation of AM, and it seems to be a safe and effective treatment for patients with PEDs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/11206721211049093","type":"journal-article","created":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T14:21:00Z","timestamp":1633962060000},"page":"2141-2147","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Sutureless \u201cContact Lens Sandwich\u201d Technique for Amniotic Membrane Therapy of Central Corneal Ulcers"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0908-9067","authenticated-orcid":false,"given":"Saverio V.","family":"Luccarelli","sequence":"first","affiliation":[{"name":"Eye Clinic San Giuseppe Hospital, IRCCS Multimedica, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3811-5893","authenticated-orcid":false,"given":"Edoardo","family":"Villani","sequence":"additional","affiliation":[{"name":"Eye Clinic San Giuseppe Hospital, IRCCS Multimedica, Milan, Italy"},{"name":"Department of Clinical Sciences and Community Health, University of Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Lucentini","sequence":"additional","affiliation":[{"name":"Eye Clinic San Giuseppe Hospital, IRCCS Multimedica, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Bonsignore","sequence":"additional","affiliation":[{"name":"Eye Clinic San Giuseppe Hospital, IRCCS Multimedica, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Sacchi","sequence":"additional","affiliation":[{"name":"Eye Clinic San Giuseppe Hospital, IRCCS Multimedica, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia Acuti","family":"Martellucci","sequence":"additional","affiliation":[{"name":"Department of Medical Science, University of Ferrara, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Nucci","sequence":"additional","affiliation":[{"name":"Eye Clinic San Giuseppe Hospital, IRCCS Multimedica, Milan, Italy"},{"name":"Department of Clinical Sciences and Community Health, University of Milan, 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