{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T13:24:37Z","timestamp":1788269077562,"version":"build-2803163510"},"reference-count":12,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T00:00:00Z","timestamp":1612915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To report the surgical outcomes of penetrating keratoplasty (PKP) and sutureless scleral fixation (SSF) using Carlevale Lens (Soleko) combined procedure to solve corneal failure and aphakia in vitrectomized eyes and discuss eventual advantages of this new approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Two patients underwent primary wound repair and pars plana vitrectomy after a penetrating ocular trauma and were referred to the author\u2019s clinic. The PKP and SSF-Carlevale lens implantation were performed under retrobulbar anesthesia. Intraoperative and postoperative complications were recorded, intraocular lens positioning was evaluated using anterior segment optical coherence tomography (AS-OCT) and endothelial cell density was determined using an endothelial microscope. Both patients completed 12\u2009months follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The surgery was performed without intraoperative complications. After 1\u2009month, the lens was fixed well, and the graft showed no sign of rejection. At the last visit after 12\u2009months, the corneal graft remained transparent with good endothelial cell density in both cases; conjunctival scarring or inflammation and plugs externalization did not occur during follow-ups. Best-corrected visual acuity was 4\/10\u2009Snellen in the first case, while in the second case, we witnessed a limited visual recovery of 1\/20\u2009Snellen due to retinal issues.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>We report the feasibility of secondary IOL implantation using Carlevale with penetrating keratoplasty. The relative of ease of Carlevale lens implantation through the transscleral plugs reduces the open globe length resulting in a safer procedure, especially for vitrectomized eyes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672121990634","type":"journal-article","created":{"date-parts":[[2021,2,13]],"date-time":"2021-02-13T06:38:54Z","timestamp":1613198334000},"page":"NP67-NP70","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Trans-scleral plugs scleral fixation IOL and penetrating keratoplasty to restore vision in vitrectomized eyes"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6969-1979","authenticated-orcid":false,"given":"Lorenzo","family":"de Angelis","sequence":"first","affiliation":[{"name":"Department of Translational Surgery and Medicine, Ophthalmology, Department of NEUROFARBA, University of Florence, Careggi, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8835-9381","authenticated-orcid":false,"given":"Francesco","family":"Barca","sequence":"additional","affiliation":[{"name":"Department of Translational Surgery and Medicine, Ophthalmology, Department of NEUROFARBA, University of Florence, Careggi, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislao","family":"Rizzo","sequence":"additional","affiliation":[{"name":"UOC Oculistica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"},{"name":"Universit\u00e0 Cattolica del Sacro Cuore, Rome, Italy"},{"name":"Consiglio Nazionale delle Ricerche, Istituto di Neuroscienze, Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Di Leo","sequence":"additional","affiliation":[{"name":"Department of Translational Surgery and Medicine, Ophthalmology, Department of NEUROFARBA, University of Florence, Careggi, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6147-8962","authenticated-orcid":false,"given":"Leandro","family":"Oliverio","sequence":"additional","affiliation":[{"name":"Department of Translational Surgery and Medicine, Ophthalmology, Department of NEUROFARBA, University of Florence, Careggi, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6902-2983","authenticated-orcid":false,"given":"Tomaso","family":"Caporossi","sequence":"additional","affiliation":[{"name":"UOC Oculistica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"},{"name":"Universit\u00e0 Cattolica del Sacro Cuore, Rome, Italy"},{"name":"Consiglio Nazionale delle Ricerche, Istituto di Neuroscienze, Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,2,10]]},"reference":[{"key":"bibr1-1120672121990634","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-018-0804-4"},{"key":"bibr2-1120672121990634","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000001716"},{"key":"bibr3-1120672121990634","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)73982-0"},{"key":"bibr4-1120672121990634","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)74784-1"},{"key":"bibr5-1120672121990634","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2005.06.010"},{"key":"bibr6-1120672121990634","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0214140"},{"key":"bibr7-1120672121990634","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000632"},{"key":"bibr8-1120672121990634","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000944"},{"key":"bibr9-1120672121990634","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S101515"},{"key":"bibr10-1120672121990634","doi-asserted-by":"publisher","DOI":"10.1097\/j.jcrs.0000000000000135"},{"key":"bibr11-1120672121990634","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-020-04789-3"},{"key":"bibr12-1120672121990634","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000002378"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672121990634","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1120672121990634","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672121990634","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:45:41Z","timestamp":1777405541000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1120672121990634"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,10]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1177\/1120672121990634"],"URL":"https:\/\/doi.org\/10.1177\/1120672121990634","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,10]]}}}