{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:38:43Z","timestamp":1777581523103,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,2,14]],"date-time":"2021-02-14T00:00:00Z","timestamp":1613260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>The purpose of this study was to examine the aetiology, investigation and management of ophthalmia neonatorum (ON) presenting to a tertiary referral children\u2019s hospital over 5\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The eye swab data of all neonates presenting to Children\u2019s Health Ireland at Temple Street (Dublin, Ireland) between 1st January 2013 and 3rd September 2018 was analysed. The medical records of all patients with positive eye swab results were retrospectively reviewed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 157 neonates had positive eye swab results. 54 cases were identified as ON. Chlamydia trachomatis (20.4%) was the most common organism identified, followed by Staphylococcus aureus (18.5%), Haemophilus influenzae (14.8%), Moraxella catarrhalis (7.4%), Streptococcus pneumoniae (5.6%), Escherischia coli (3.7%), Klebsiella pneumoniae (1.9%) and Pseudomonas aeruginosa (1.9%). A bacterial culture swab was tested in all cases (100%), a C. trachomatis\/N. gonorrhoeae PCR swab in 70.4% and a viral PCR swab in 35.2%. On subanalysis of the cases that had C. trachomatis\/N. gonorrhoeae PCR testing, C. trachomatis was responsible for 28.9% of cases. 50% of cases were hospitalised, intravenous antibiotics were administered in 46.3% and macrolide therapy was prescribed in 38.9%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>C. trachomatis was the most common cause of ON in this study and may be responsible for an even higher proportion of cases due to incomplete testing. In keeping with studies in different populations, S. aureus, H. influenzae and S. pneumoniae were also common. As a result, an improved management algorithm for cases of ON has been introduced in this centre.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1120672121994734","type":"journal-article","created":{"date-parts":[[2021,2,15]],"date-time":"2021-02-15T00:09:15Z","timestamp":1613347755000},"page":"587-591","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Ophthalmia neonatorum in a tertiary referral children\u2019s hospital: A retrospective study"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3011-2033","authenticated-orcid":false,"given":"David","family":"Gildea","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Children\u2019s Health Ireland at Temple Street, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinold","family":"Goetz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Children\u2019s Health Ireland at Temple Street, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Drew","sequence":"additional","affiliation":[{"name":"Children\u2019s Health Ireland at Temple Street, Dublin, Ireland"},{"name":"Irish Meningitis and Sepsis Reference Laboratory, Children\u2019s Health Ireland at Temple Street, Dublin, Ireland"},{"name":"Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Chamney","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Children\u2019s Health Ireland at Temple Street, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,2,14]]},"reference":[{"key":"bibr1-1120672121994734","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2002.800212.x"},{"key":"bibr2-1120672121994734","doi-asserted-by":"publisher","DOI":"10.1097\/00006565-200302000-00014"},{"key":"bibr3-1120672121994734","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2007.12.003"},{"key":"bibr4-1120672121994734","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-016-3274-5"},{"key":"bibr5-1120672121994734","doi-asserted-by":"publisher","DOI":"10.1097\/00004397-199030010-00018"},{"key":"bibr6-1120672121994734","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir699"},{"key":"bibr7-1120672121994734","doi-asserted-by":"publisher","DOI":"10.1053\/j.spid.2005.06.004"},{"issue":"11","key":"bibr8-1120672121994734","first-page":"1187","volume":"59","author":"Matejcek A","year":"2013","journal-title":"Can Fam Physician"},{"key":"bibr9-1120672121994734","doi-asserted-by":"publisher","DOI":"10.1053\/j.spid.2005.06.006"},{"key":"bibr10-1120672121994734","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-011-0167-y"},{"key":"bibr11-1120672121994734","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2010.531326"},{"issue":"1","key":"bibr12-1120672121994734","first-page":"27","volume":"12","author":"Chang K","year":"2006","journal-title":"Hong Kong Med J"},{"key":"bibr13-1120672121994734","doi-asserted-by":"publisher","DOI":"10.1016\/S1201-9712(01)90088-8"},{"issue":"2","key":"bibr14-1120672121994734","volume":"14","author":"Amini E","year":"2008","journal-title":"Med Sci Monit"},{"key":"bibr15-1120672121994734","doi-asserted-by":"publisher","DOI":"10.1542\/peds.76.2.172"},{"key":"bibr16-1120672121994734","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2013-305271"},{"key":"bibr17-1120672121994734","unstructured":"Public Health England. UK standards for microbiology investigations: conjunctivitis. 2014. S 3 Issue 1.2. https:\/\/assets.publishing.service.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/455111\/S_3i1.2.pdf"},{"key":"bibr18-1120672121994734","unstructured":"Departments of Pharmacy, Infectious Diseases and Microbiology Children\u2019s Health Ireland at Crumlin Temple Street and Tallaght. Eye, Conjunctivitis. Children\u2019s Health Ireland - Antimicrobial Guidelines 2018. https:\/\/www.olchc.ie\/Healthcare-Professionals\/Clinical-Guidelines\/Antimicrobial-Guidelines-2020.pdf"},{"key":"bibr19-1120672121994734","volume-title":"Chlamydia and Lymphogranuloma venereum (LGV) in Ireland, 2018","author":"HSE Health Protection Surveillance Centre","year":"2019"},{"key":"bibr20-1120672121994734","volume-title":"Gonorrhoea in Ireland, 2018","author":"HSE Health Protection Surveillance Centre","year":"2019"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672121994734","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1120672121994734","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1120672121994734","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:45:49Z","timestamp":1777405549000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1120672121994734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,14]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1177\/1120672121994734"],"URL":"https:\/\/doi.org\/10.1177\/1120672121994734","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,14]]}}}